5-BROMO-2-METHYLPYRIDIN-3-AMINE Chemical Properties

Melting point:

108-109℃

Boiling point:

283.5±35.0 °C(Predicted)

Density 

1.593±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

form 

crystalline solid

pka

4.53±0.20(Predicted)

color 

Off-white

Safety Information

Risk Statements 

41

Safety Statements 

26-39

HazardClass 

IRRITANT

HS Code 

2933399990

5-BROMO-2-METHYLPYRIDIN-3-AMINE Usage And Synthesis

Description

5-Bromo-2-methylpyridin-3-amine is also named as 3-Amino-5-bromo-2-methylpyridine. It can be converted to 5-bromo-2-methyl-3-pyridinol by diazotization with sodium nitrite in aqueous sulfuric acid. 5-Bromo-2-methyl-3-pyridinol can be used to make brominated dihydropyridines, which are substrates for the palladium catalyzed coupling, a process to produce compounds for the treatment of patients with disorders, such as central nervous system disorders.

Reference

G. Dull, J. Munoz, J. Genus, J. Moore, Hydroxybenzoate salts of metanicotine compounds, Patent US20060122239A1

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