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Sodium lauroylsarcosinate

Basic information Uses Application Safety Supplier Related

Sodium lauroylsarcosinate Basic information

Product Name:
Sodium lauroylsarcosinate
Synonyms:
  • n-methyl-n-(1-oxododecyl)glycine sodium salt
  • N-LAURYL SARCOSINE, SODIUM SALT
  • N-LAUROYLSARCOSINE NA-SALT
  • N-LAUROYLSARCOSINE SODIUM SALT
  • N-LAUROYLSARCOSINE SODIUM SALT HYDRATE
  • GARDOL
  • LAUROYLSARCOSINE, SODIUM SALT
  • N-Methylglycinol
CAS:
137-16-6
MF:
C15H28NO3.Na
MW:
293.38
EINECS:
205-281-5
Product Categories:
  • detergent
  • Amino ACIDS SERIES
  • Additional Anionic DetergentsDetergents
  • Anionic
  • Detergents
  • Detergents A to Z
  • Anionic Surfactants
  • Carboxylate (Surfactants)
  • Functional Materials
  • Surfactants
  • Biochemistry
  • Nonionic Surfactants (for Biochemistry)
  • Surfactants (for Biochemistry)
  • Cosmetic Ingredients & Chemicals
  • Hair Care
  • Oral Care
  • Skin Care
  • 137-16-6
Mol File:
137-16-6.mol
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Sodium lauroylsarcosinate Chemical Properties

Melting point:
46 °C
Density 
1.033 g/mL at 20 °C
vapor pressure 
0.02 hPa (20 °C)
RTECS 
MC0598960
Flash point:
267℃
storage temp. 
room temp
solubility 
H2O: 1 M at 20 °C, clear, colorless
form 
Powder
Specific Gravity
1.03 (20/4℃)
color 
White
Odor
at 100.00?%. bland
PH
7.0-9.0 (25℃, 1M in H2O)
Water Solubility 
Soluble in water (293 g/L).
Sensitive 
Hygroscopic
λmax
λ: 260 nm Amax: 0.2
λ: 280 nm Amax: 0.06
Merck 
14,4368
BRN 
5322974
Stability:
Stable. Incompatible with strong oxidizing agents.
LogP
0.37
CAS DataBase Reference
137-16-6(CAS DataBase Reference)
EPA Substance Registry System
Sodium N-lauroylsarcosinate (137-16-6)
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Safety Information

Hazard Codes 
Xi,T
Risk Statements 
36/37/38-41-38-23
Safety Statements 
22-24/25-36/37/39-27-26-45-38-37/39
RIDADR 
UN 2811 6.1 / PGII
WGK Germany 
3
3-10
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
II
HS Code 
34021190
Toxicity
LD50 orally in Rabbit: 2888 mg/kg

MSDS

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Sodium lauroylsarcosinate Usage And Synthesis

Uses

Sodium lauroyl sarcosinate (INCI), also known as sarkosyl, is a white powder derived from sarcosine, which make it is fate-free and biodegradable. The surfactant is amphiphilic due to the hydrophobic 12-carbon chain (lauroyl) and the hydrophilic carboxylate.
Sodium lauroyl sarcosinate is personal care products as well as in household and industrial applications, and it is used as a co-surfactant in cleanser formulations such as shampoos and body washes. It can also be used in oral care applications such as toothpastes and incorporated into syndet and combo bars. The typical usage levels range from 1-5% on an active basis.

Application

Sodium lauroyl sarcosinate (INCI) is mild, biodegradable anionic surfactants derived from sarcosine used as a foaming and cleansing agent in shampoo, shaving foam, toothpaste, and foam wash products. The surfactant is amphiphilic due to the hydrophobic 12-carbon chain (lauroyl) and the hydrophilic carboxylate.
Sodium lauroyl sarcosinate is a high foam, eco-friendly surfactant. It has good chlorine stability with anti-corrosion properties. This surfactant has excellent ocular tolerance and gentleness. Sodium lauroyl sarcosinate is often seen in shampoos, bath, cleansing and shaving products as a foaming agent, surfactant, and hair conditioning agent. Sodium lauroyl sarcosinate has the ability to enhance the appearance and feel of hair by improving body, suppleness and sheen, especially in hair that is chemically damaged. This ingredient also serves to clean skin and hair by mixing with oil and dirt and enabling them to be rinsed away. As a modified fatty acid, it is thought to be more soluble, and have increased crystallinity and acidity compared to its original fatty acid composition.

Chemical Properties

white powder

Uses

N-Lauroylsarcosine is used for solubilization and separation of membrane proteins and glycoprotein's; reported to inhibit hexokinase. It is useful in concentrated salt solutions used in the cell lysis step during RNA purification (helps avoid excessive foaming). It has been used to indicate paramagnetic anisotropy sign change in micelle mesophage. Inhibits bacterial flora of human saliva/gut at 0.25% as well as acting as a fungi static agent in aqueous dispersion (1%).

Uses

Detergent, foaming agent, antienzyme for dentifrices: King, US 2689170 (1954 to Colgate-Palmolive).

Uses

Suitable for

  • solubilization and separation of membrane proteins
  • lysis of cells during the isolation of RNA
  • inhibition of hexokinase

General Description

N-Lauroylsarcosine is an anionic surfactant with an ability to denature proteins. Due to its microbicidal property, N-lauroylsarcosine is being considered as a potent anti-microbicide in topical formulations, especially against sexually transmitted diseases (STDs).

Flammability and Explosibility

Non flammable

Biochem/physiol Actions

N-Lauroylsarcosine is an anionic surfactant which also has protein denaturant potency. In addition, it has been shown as a microbicide for sexually transmitted diseases.

Sodium lauroylsarcosinate Preparation Products And Raw materials

Raw materials

Sodium lauroylsarcosinateSupplier

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