Sodium N-lauroylsarcosinate Chemical Properties

Melting point:

46 °C

Density 

1.033 g/mL at 20 °C

vapor pressure 

0.02 hPa (20 °C)

RTECS 

MC0598960

Flash point:

267℃

storage temp. 

room temp

solubility 

H₂O: 1 M at 20 °C, clear, colorless

form 

Powder

Specific Gravity

1.03 (20/4℃)

color 

White

Odor

at 100.00?%. bland

PH

7.0-9.0 (25℃, 1M in H2O)

Water Solubility 

Soluble in water (293 g/L).

Sensitive 

Hygroscopic

λmax

λ: 260 nm Amax: 0.2
λ: 280 nm Amax: 0.06

Merck 

14,4368

BRN 

5322974

Stability:

Stable. Incompatible with strong oxidizing agents.

LogP

0.37

CAS DataBase Reference

137-16-6(CAS DataBase Reference)

EPA Substance Registry System

Sodium N-lauroylsarcosinate (137-16-6)

Safety Information

Hazard Codes 

Xi,T

Risk Statements 

36/37/38-41-38-23

Safety Statements 

22-24/25-36/37/39-27-26-45-38-37/39

RIDADR 

UN 2811 6.1 / PGII

WGK Germany 

3

F 

3-10

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

II

HS Code 

34021190

Toxicity

LD50 orally in Rabbit: 2888 mg/kg

MSDS

• Language:English Provider:Sodium lauroylsarcosinate
• Language:English Provider:SigmaAldrich

Sodium N-lauroylsarcosinate Usage And Synthesis

Uses

Sodium lauroyl sarcosinate (INCI), also known as sarkosyl, is a white powder derived from sarcosine, which make it is fate-free and biodegradable. The surfactant is amphiphilic due to the hydrophobic 12-carbon chain (lauroyl) and the hydrophilic carboxylate.
Sodium lauroyl sarcosinate is personal care products as well as in household and industrial applications, and it is used as a co-surfactant in cleanser formulations such as shampoos and body washes. It can also be used in oral care applications such as toothpastes and incorporated into syndet and combo bars. The typical usage levels range from 1-5% on an active basis.

Application

Sodium lauroyl sarcosinate (INCI; Sodium N-lauroylsarcosinate) is mild, biodegradable anionic surfactants derived from sarcosine used as a foaming and cleansing agent in shampoo, shaving foam, toothpaste, and foam wash products. The surfactant is amphiphilic due to the hydrophobic 12-carbon chain (lauroyl) and the hydrophilic carboxylate. Sodium lauroyl sarcosinate is a high foam, eco-friendly surfactant. It has good chlorine stability with anti-corrosion properties. This surfactant has excellent ocular tolerance and gentleness. Sodium lauroyl sarcosinate is often seen in shampoos, bath, cleansing and shaving products as a foaming agent, surfactant, and hair conditioning agent. Sodium lauroyl sarcosinate has the ability to enhance the appearance and feel of hair by improving body, suppleness and sheen, especially in hair that is chemically damaged. This ingredient also serves to clean skin and hair by mixing with oil and dirt and enabling them to be rinsed away. As a modified fatty acid, it is thought to be more soluble, and have increased crystallinity and acidity compared to its original fatty acid composition.

Chemical Properties

white powder

Occurrence

Sodium Lauroyl Sarcosinate (Sodium N-lauroylsarcosinate) is a natural ingredient that is derived from coconuts. However, it can also be made synthetically.

Uses

Detergent, foaming agent, antienzyme for dentifrices: King, US 2689170 (1954 to Colgate-Palmolive).

Uses

Suitable for

• solubilization and separation of membrane proteins
• lysis of cells during the isolation of RNA
• inhibition of hexokinase

Uses

N-Lauroylsarcosine (Sodium N-lauroylsarcosinate) is used for solubilization and separation of membrane proteins and glycoprotein's; reported to inhibit hexokinase. It is useful in concentrated salt solutions used in the cell lysis step during RNA purification (helps avoid excessive foaming). It has been used to indicate paramagnetic anisotropy sign change in micelle mesophage. Inhibits bacterial flora of human saliva/gut at 0.25% as well as acting as a fungi static agent in aqueous dispersion (1%).

General Description

N-Lauroylsarcosine (Sodium N-lauroylsarcosinate) is an anionic surfactant with an ability to denature proteins. Due to its microbicidal property, N-lauroylsarcosine is being considered as a potent anti-microbicide in topical formulations, especially against sexually transmitted diseases (STDs).

Flammability and Explosibility

Non flammable

Biochem/physiol Actions

N-Lauroylsarcosine is an anionic surfactant which also has protein denaturant potency. In addition, it has been shown as a microbicide for sexually transmitted diseases.

Safety Profile

Sodium Lauroyl Sarcosinate is good for skin and hair. It does not have any common side effects like skin irritation and sensitivity. Sodium Lauroyl Sarcosinate is also vegan and can be added in concentrations of up to 5% in leave-on products and 15% in rinse-off products. Further, this ingredient is non-comedogenic, so it does not clog pores or cause acne. Sodium Lauroyl Sarcosinate can be used on all skin types. However, a patch test is recommended.

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