O-(2-AMINOETHYL)-O-(2-(BOC-AMINO)ETHYL)OCTAETHYLENE GLYCOL
O-(2-AMINOETHYL)-O-(2-(BOC-AMINO)ETHYL)OCTAETHYLENE GLYCOL Basic information
- Product Name:
- O-(2-AMINOETHYL)-O-(2-(BOC-AMINO)ETHYL)OCTAETHYLENE GLYCOL
- Synonyms:
-
- NHBoc-PEG9-amine
- tert-butyl N-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate
- boc-peg-amine (n=9)
- O-(2-AMinoethyl )-O`-[2-(Boc-aMino)ethyl ]octaaethylene glycol
- Boc-NH-PEG9-CH2CH2NH2
- 31-Amino-5,8,11,14,17,20,23,26,29-nonaoxa-2-azahentriacontanoic acid 1,1-dimethylethyl ester
- 5,8,11,14,17,20,23,26,29-Nonaoxa-2-azahentriacontanoicacid, 31-amino-, 1,1-dimethylethyl ester
- t-Boc-N-amido-PEG9-Amine
- CAS:
- 890091-43-7
- MF:
- C25H52N2O11
- MW:
- 556.69
- Product Categories:
-
- Chemical Biology
- Chemical Synthesis
- Heterobifunctional PEGs
- High Oligomer Purity PEG
- Materials Science
- PEGylation
- Poly(ethylene glycol) and Poly(ethylene oxide)
- Polymer Science
- Polymers
- peg
- Mol File:
- 890091-43-7.mol
O-(2-AMINOETHYL)-O-(2-(BOC-AMINO)ETHYL)OCTAETHYLENE GLYCOL Chemical Properties
- Boiling point:
- 609.8±55.0 °C(Predicted)
- Density
- 1.082±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Soluble in Water, DMSO, DMF, DCM
- form
- Liquid
- pka
- 12.23±0.46(Predicted)
- color
- Colorless to light yellow
- InChI
- InChI=1S/C25H52N2O11/c1-25(2,3)38-24(28)27-5-7-30-9-11-32-13-15-34-17-19-36-21-23-37-22-20-35-18-16-33-14-12-31-10-8-29-6-4-26/h4-23,26H2,1-3H3,(H,27,28)
- InChIKey
- RTTGVFBQUXJWJG-UHFFFAOYSA-N
- SMILES
- C(OC(C)(C)C)(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN
O-(2-AMINOETHYL)-O-(2-(BOC-AMINO)ETHYL)OCTAETHYLENE GLYCOL Usage And Synthesis
Description
t-Boc-N-amido-PEG9-amine is a monodisperse PEG reagent containing an amino group and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Uses
Boc-amido-PEG9-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
General Description
Our highly purified mono-protected homobifunctional polyethylene glycols display oligomer purities of more than 90%. This extremely narrow distribution of oligomers ensures homogeneous products in many applications such as conjugation reactions or introduction of solubilizing units or spacers.
reaction suitability
reagent type: cross-linking reagent
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
O-(2-AMINOETHYL)-O-(2-(BOC-AMINO)ETHYL)OCTAETHYLENE GLYCOLSupplier
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O-(2-AMINOETHYL)-O-(2-(BOC-AMINO)ETHYL)OCTAETHYLENE GLYCOL(890091-43-7)Related Product Information
- O-(2-AMINOETHYL)-O-(2-AZIDOETHYL)HEPTAETHYLENE GLYCOL
- O-[2-(Boc-amino)ethyl]-Oμ-(2-carboxyethyl)polyethylene glycol 3,000
- BOC-21-AMINO-4,7,10,13,16,19-HEXAOXAHENEICOSANOIC ACID
- t-Boc-N-amido-PEG5-acid
- Boc-9-AMino-4,7-Dioxanonanoic acid
- t-boc-N-amido-PEG14-amine
- O-(2-AMINOETHYL)-O'-(2-(BOC-AMINO)ETHYL)
- t-Boc-N-amido-PEG17-acid
- t-boc-N-amido-PEG13-amine
- t-Boc-N-amido-PEG2-acid
- t-Boc-N-amido-PEG14-acid
- t-boc-N-amido-PEG16-amine
- t-Boc-N-amido-PEG11-acid
- 22-Amino-5,8,11,14,17,20-hexaoxa-2-azadocosanoic acid 1,1-dimethylethyl ester
- t-Boc-Amido-PEG28-Amine
- t-Boc-Amido-PEG20-Amine
- t-Boc-Amido-PEG36-Amine
- Carbamic acid, [2-(2-aminoethoxy)ethyl]-, 1,1-dimethylethyl ester (9CI)