ICI D 6888
ICI D 6888 Basic information
- Product Name:
- ICI D 6888
- Synonyms:
-
- ICI D 6888
- ICI-D-6888
- ZD 6888
- ZD6888
- ZD-6888
- ZD-6888 HCl
- ZD-6888 Hydrochloride
- ZD 6888 Hydrochloride,ZD6888 Hydrochloride
- CAS:
- 138620-17-4
- MF:
- C25H26ClN5O
- MW:
- 447.97
- Mol File:
- 138620-17-4.mol
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ICI D 6888 Usage And Synthesis
Uses
ZD-6888 hydrochloride (ICI-D 6888 hydrochloride) is an antagonist for angiotensin II, which competitively inhibits the angiotensin II-mediated release of renin, affects the renal structure and function[1].
References
[1] Jackson DG, et al., Histopathological and ultrastructural changes in the juxtaglomerular apparatus of the rat following administration of ZENECA ZD6888 (2-ethyl-5,6,7,8-tetrahydro-4-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)- methoxy]quinoline), an angiotensin II antagonist. Toxicol Pathol. 1995 Jan-Feb;23(1):7-15. DOI:10.1177/019262339502300102