1,1-Bis(4-methoxyphenyl)-2-propyn-1-ol Chemical Properties

Melting point:

91.9-92.2℃

Boiling point:

412.0±45.0 °C(Predicted)

Density 

1.156

storage temp. 

2-8°C

form 

powder to crystal

pka

11.72±0.29(Predicted)

color 

White to Almost white

Safety Information

HS Code 

2909.49.1500

1,1-Bis(4-methoxyphenyl)-2-propyn-1-ol Usage And Synthesis

Uses

1,1-bis(4-Methoxyphenyl)-2-propyn-1-ol (cas# 101597-25-5) is used in the synthetic preparation of photochromic pyranobenzopyran derivatives.

Preparation

The preparation of 1,1-bis(4-methoxyphenyl)-2-propyn-1-ol is as follows:18W % sodium acetylide in xylene/mineral oil 121.1mL (0.45mol, 1eq) was dissolved in anhydrous THF (1L) saturated with acetylene gas. After that 4,4-dimethoxybenzophenone 100g (0.41mol, 1eq) was put inside the reaction mixture under nitrogen and stirred for 24h at room temperature. The product was extracted by solvent extraction using ethyl acetate and water, organic layer was dried with MgSO4 and solid product on vacuum drier. After complete drying, the product again dissolve in ethyl acetate and poured into 1L hexane slowly under stirring which afford 8 as white color solid, yield (99g, 90%).

1,1-Bis(4-methoxyphenyl)-2-propyn-1-ol(101597-25-5)Related Product Information

• 1,1,4,4-TETRAPHENYL-2-BUTYN-1,4-DIOL
• 1,1-DIPHENYL-2-PROPYN-1-OL
• 1,1'-THIOCARBONYLDI-2(1H)-PYRIDONE
• 1,1-Di-p-tolyl-2-propyn-1-ol
• cis-2-tert-Butyl-2-butenedinitrile
• 1,2-BIS-(4-FLUOROPHENYL)ETHANONE