INDOMETHACIN SODIUM
INDOMETHACIN SODIUM Basic information
- Product Name:
- INDOMETHACIN SODIUM
- Synonyms:
-
- 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1h-indole-3-aceticacisodiumsalt
- 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-indole-3-aceticacisodiumsalt
- osmosin
- sodium1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1h-indole-3-acetate
- sodiumindomethacin
- 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid sodium salt
- IndoMetacine sodiuM
- 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-Methoxy-2-Methyl-, sodiuM salt
- CAS:
- 7681-54-1
- MF:
- C19H15ClNNaO4
- MW:
- 379.77
- EINECS:
- 231-670-4
- Mol File:
- 7681-54-1.mol
More
Less
INDOMETHACIN SODIUM Chemical Properties
- storage temp.
- Sealed in dry,Room Temperature
- form
- Powder
- InChI
- InChI=1S/C19H16ClNO4.Na/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12;/h3-9H,10H2,1-2H3,(H,22,23);/q;+1/p-1
- InChIKey
- JMHRGKDWGWORNU-UHFFFAOYSA-M
- SMILES
- C12C=CC(OC)=CC=1C(=C(C)N2C(=O)C1C=CC(Cl)=CC=1)CC([O-])=O.[Na+]
More
Less
INDOMETHACIN SODIUM Usage And Synthesis
Description
Indomethacin sodium is a potent, orally active COX1/2 inhibitor with IC50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin sodium has anticancer activity and anti-infective activity. Indomethacin sodium can be used for cancer, inflammation and viral infection research.
Uses
Anti-inflammatory.
brand name
Indocin (Ovation).
IC 50
COX-1: IC50 = 0.1 μM (sheep); Cox-1: IC50 = 1.67 μM (human);
COX-2: IC50 = 6 μM (sheep); Cox-2: IC50 = 24.6 μM (human)
INDOMETHACIN SODIUMSupplier
Hangzhou Yuhao Chemical Technology Co., Ltd
- Tel
- 0571-82693216
- info@yuhaochemical.com
Wuhan Fortuna Chemical Co., Ltd
- Tel
- 027-59207852 13308628970
- buy@fortunachem.com
Hangzhou Sage Chemical Co., Ltd.
- Tel
- +86057186818502 13588463833
- info@sagechem.com
Hubei XinyuanShun Chemical Co., Ltd.
- Tel
- 13971561712, 13995564702, 027-50664929
- hbeixys2001@163.com
Hubei Jusheng Technology Co.,Ltd
- Tel
- 027-59599241 18871490274
- 1400878000@qq.com