Ansuvimab
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Ansuvimab Chemical Properties
- form
- Liquid
- color
- Colorless to light yellow
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Ansuvimab Usage And Synthesis
Uses
Ansuvimab (Ansuvimab-zyk) is a recombinant human monoclonal IgG1 antibody that exhibits antiviral activity against Zaire ebolavirus. Ansuvimab binds to the glycoprotein on Zaire ebolavirus to block its entry into host cells[1].
in vivo
Ansuvimab results in all macaques surviving after exposure to a lethal dose of Ebola virus in on day 0[1].
IC 50
ZEBOV
References
[1] Lee A, et, al. Ansuvimab: First Approval. Drugs. 2021 Apr;81(5):595-598. DOI:10.1007/s40265-021-01483-4
[2] Corti D, et, al. Protective monotherapy against lethal Ebola virus infection by a potently neutralizing antibody. Science. 2016 Mar 18;351(6279):1339-42. DOI:10.1126/science.aad5224
AnsuvimabSupplier
ShangHai Biochempartner Co.,Ltd
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Guangzhou Hongyuan Chemical Co.,Ltd
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Biolab Reagents
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Wanxin Biotechnology (Jiaxing) Co., LTD
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