LY 267108
LY 267108 Basic information
- Product Name:
- LY 267108
- Synonyms:
-
- LY 267108
- (2R,3R,6R,7S,8S,9R,10R)-7-[(2,6-Dideoxy-3-C-Methyl-3-O-Methyl-α-L-ribo-hexopyranosyl)oxy]-3-[(1R,2R)-1,2-dihydroxy-1-Methylbutyl]-2,6,8,10,12-pentaMethyl-9-[[3,4,6-trideoxy-3-(diMethylaMino)-β-D-xylo-hexopyranosyl]oxy]-4,13-dioxabicyclo[8.2.1]tridec-12-en-5-one
- 8,9-Anhydropseudo-erythroMycin A-6,9-heMiketal
- (2R,3R,6R,7S,8S,9R,10R)-7-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy]-3-[(1R,2R)-1,2-dihydroxy-1-methylbutyl]-2,6,8,10,12-pentamethyl-9-[[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy]-4,13-dioxabicyclo[8.2.1]tridec-12-en-5-one
- NMIWBQUQCOMGHJ-XWVSLMRSSA-N
- Erythromycin EP Impurity F/(2R,3R,6R,7S,8S,9R,10R)-3-((2R,3R)-2,3-dihydroxypentan-2-yl)-9-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-7-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-2,6
- Erythromycin Impurit F:(pseudoerythromycin A enol ether)
- Erythromycin Impurity 15(Erythromycin EP Impurity F)
- CAS:
- 105882-69-7
- MF:
- C37H65NO12
- MW:
- 715.91
- Product Categories:
-
- Intermediates & Fine Chemicals
- Metabolites & Impurities
- Chromatography
- Drugs&Metabolites
- Forensic and Veterinary Standards
- Pharmaceuticals
- Neat CompoundsAnalytical Standards
- Pharmacology Standards
- Mol File:
- 105882-69-7.mol
LY 267108 Chemical Properties
- Melting point:
- 127.0-130.0 °C
- Boiling point:
- 810.7±65.0 °C(Predicted)
- Density
- 1.20±0.1 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
- pka
- 13.45±0.70(Predicted)
LY 267108 Usage And Synthesis
Chemical Properties
White Solid
Uses
Pseudo Erythromycin A Enol Ether (Erythromycin EP Impurity F) is an Erythromycin impurity.
Uses
Erythromycin impurity.
Uses
Pseudoerythromycin A enol ether is a degradation product of erythromycin formed by a complex internal rearrangement of erythromycin A on exposure to neutral to weakly alkaline conditions. The C6–OH forms an internal enol ether with the C9 ketone of erythromycin, while the C11-OH attacks the carbonyl of the lactone to reduce the macrocycle from a 14- to an 11-membered macrolide. Synthetically, pseudoerythromycin A enol ether is prepared by reacting erythromycin enol ether with carbonate. Pseudoerythromycin A enol ether is devoid of antibiotic activity but is an important analytical standard for erythromycin A stability studies.
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