L-Glutamic acid, L-α-aspartyl-L-leucyl-L-α-aspartyl-L-valyl-L-prolyl-L-isoleucyl-L-prolylglycyl-L-arginyl-L-phenylalanyl-L-α-aspartyl-L-arginyl-L-arginyl-L-valyl-O-phosphono-L-seryl-L-valyl-L-alanyl-L-alanyl- Chemical Properties

Density 

1.52±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

Sequence

Asp-Leu-Asp-Val-Pro-Ile-Pro-Gly-Arg-Phe-Asp-Arg-Arg-Val-{pSer}-Val-Ala-Ala-Glu

L-Glutamic acid, L-α-aspartyl-L-leucyl-L-α-aspartyl-L-valyl-L-prolyl-L-isoleucyl-L-prolylglycyl-L-arginyl-L-phenylalanyl-L-α-aspartyl-L-arginyl-L-arginyl-L-valyl-O-phosphono-L-seryl-L-valyl-L-alanyl-L-alanyl- Usage And Synthesis

Uses

PKA Regulatory Subunit II Substrate (RII phosphopeptide) is a tool peptide derived from the regulatory subunit Type II (RII) of cyclic AMP-dependent protein kinase (PKA). PKA Regulatory Subunit II Substrate is commonly used to mimic the phosphorylation of protein kinases and as a specific substrate for protein phosphatases to assess the activities of these enzymes[1].

References

[1] Wang Lu, et al. "A novel peptide exerts potent immunosuppression by blocking the two-site interaction of NFAT with calcineurin." Journal of Biological Chemistry 295.9 (2020): 2760-2770. DOI:10.1074/jbc.RA119.010254

L-Glutamic acid, L-α-aspartyl-L-leucyl-L-α-aspartyl-L-valyl-L-prolyl-L-isoleucyl-L-prolylglycyl-L-arginyl-L-phenylalanyl-L-α-aspartyl-L-arginyl-L-arginyl-L-valyl-O-phosphono-L-seryl-L-valyl-L-alanyl-L-alanyl-(103659-06-9)Related Product Information

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