Ac-D-W-F-K-A-F-Y-D-K-V-A-E-K-F-K-E-A-F-NH2 Chemical Properties

Boiling point:

2350.4±65.0 °C(Predicted)

Density 

1.308±0.06 g/cm3(Predicted)

pka

4.19±0.10(Predicted)

Ac-D-W-F-K-A-F-Y-D-K-V-A-E-K-F-K-E-A-F-NH2 Usage And Synthesis

Uses

APL180 (L-4F) is an apolipoprotein A-I mimic peptide, that improves the anti-inflammatory activity of high-density lipoprotein (HDL). APL180 can be used in researches of cardiovascular diseases[1].

References

[1] Watson CE, et al., Treatment of patients with cardiovascular disease with L-4F, an apo-A1 mimetic, did not improve select biomarkers of HDL function. J Lipid Res. 2011 Feb;52(2):361-73. DOI:10.1194/jlr.M011098

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