RIBONUCLEASE INHIBITOR Chemical Properties

Density 

1.00 g/mL at 20 °C

storage temp. 

-20°C

form 

solution (clear, colorless)

biological source

human placenta

Safety Information

Hazard Codes 

B

Safety Statements 

24/25

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

RIBONUCLEASE INHIBITOR Usage And Synthesis

Uses

Useful for in vitro inhibition of ribonucleases, including procedures like cDNA synthesis, RT-PCR, and in vitro transcription and translation.

General Description

Ribonuclease inhibitor works to inhibit RNase activity by forming a tight, non-covalent 1:1 complex. It is human placenta. It inhibits RNases A, B, and C. It will not inhibit RNases H, 1, T1, S1 Nuclease, SP6, T7 RNA Polymerase, T3 RNA Polymerase, AMV Reverse Transcriptase, M-MLV Reverse Transcriptase, or Taq Polymerase. The inhibitor can be removed by phenol extraction or by heating to 65°C for 10 minutes.

Biochem/physiol Actions

Inhibits RNase by forming a tight, non-covalent 1:1 complex.

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