Basic information Safety Supplier Related

(+/-)-CGP-12177 HYDROCHLORIDE

Basic information Safety Supplier Related

(+/-)-CGP-12177 HYDROCHLORIDE Basic information

Product Name:
(+/-)-CGP-12177 HYDROCHLORIDE
Synonyms:
  • (+/-)-CGP-12177 HYDROCHLORIDE
  • CGP 12177 HYDROCHLORIDE
  • 4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE HYDROCHLORIDE
  • CGP12177HCl
  • CGP 12177 hydochloride
  • CGP 12177
  • 4-(3-tert-Butylamino-2-Hydroxypropoxy)benzimidazol-2-One
  • 4-(3-tert-Butylamino-2-hydroxypropoxy)-1H-benzimidazol-2(3H)-one
CAS:
81047-99-6
MF:
C14H21N3O3
MW:
279.33
Product Categories:
  • Adrenoceptor
Mol File:
81047-99-6.mol
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(+/-)-CGP-12177 HYDROCHLORIDE Chemical Properties

Melting point:
>256°C (dec.)
Boiling point:
376.3±37.0 °C(Predicted)
Density 
1.179
storage temp. 
Store at RT
solubility 
DMSO: >10 mg/mL
form 
solid
pka
11.48±0.30(Predicted)
color 
white
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Safety Information

WGK Germany 
3

MSDS

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(+/-)-CGP-12177 HYDROCHLORIDE Usage And Synthesis

Uses

CGP 12177 Hydrochloride is a selective β3-adrenoceptor agonist.

Definition

ChEBI: A benzimidazole that is benzimidazol-2-one substituted at position 4 by a 3-(tert-butylamino)-2-hydroxypropoxy group.

Biological Activity

Partial agonist at β 3 -adrenoceptors. β 1 - and β 2 -adrenoceptor antagonist (K i values are 0.9, 4 and 88 nM for β 1 , β 2 and β 3 receptors respectively).

(+/-)-CGP-12177 HYDROCHLORIDESupplier

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