(+/-)-CGP-12177 HYDROCHLORIDE
(+/-)-CGP-12177 HYDROCHLORIDE Basic information
- Product Name:
- (+/-)-CGP-12177 HYDROCHLORIDE
- Synonyms:
-
- (+/-)-CGP-12177 HYDROCHLORIDE
- CGP 12177 HYDROCHLORIDE
- 4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE HYDROCHLORIDE
- CGP12177HCl
- CGP 12177 hydochloride
- CGP 12177
- 4-(3-tert-Butylamino-2-Hydroxypropoxy)benzimidazol-2-One
- 4-(3-tert-Butylamino-2-hydroxypropoxy)-1H-benzimidazol-2(3H)-one
- CAS:
- 81047-99-6
- MF:
- C14H21N3O3
- MW:
- 279.33
- Product Categories:
-
- Adrenoceptor
- Mol File:
- 81047-99-6.mol
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(+/-)-CGP-12177 HYDROCHLORIDE Chemical Properties
- Melting point:
- >256°C (dec.)
- Boiling point:
- 376.3±37.0 °C(Predicted)
- Density
- 1.179
- storage temp.
- Store at RT
- solubility
- DMSO: >10 mg/mL
- form
- solid
- pka
- 11.48±0.30(Predicted)
- color
- white
MSDS
- Language:English Provider:SigmaAldrich
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(+/-)-CGP-12177 HYDROCHLORIDE Usage And Synthesis
Uses
CGP 12177 Hydrochloride is a selective β3-adrenoceptor agonist.
Definition
ChEBI: A benzimidazole that is benzimidazol-2-one substituted at position 4 by a 3-(tert-butylamino)-2-hydroxypropoxy group.
Biological Activity
Partial agonist at β 3 -adrenoceptors. β 1 - and β 2 -adrenoceptor antagonist (K i values are 0.9, 4 and 88 nM for β 1 , β 2 and β 3 receptors respectively).
(+/-)-CGP-12177 HYDROCHLORIDESupplier
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(+/-)-CGP-12177 HYDROCHLORIDE(81047-99-6)Related Product Information
- 2-(TERT-BUTYLAMINO)ETHANOL
- 2,3-Diaminophenol
- 3-AMINO-1-PHENOXY-2-PROPANOL HYDROCHLORIDE, 98
- 2-Hydroxybenzimidazole
- 3-HYDROXYPHENYLUREA
- 2H-Benzimidazol-2-one,1,3-dihydro-4-methoxy-(9CI)
- 2-(3-aminophenoxy)-1-ethanol
- N-methyl-N-(3-phenoxypropyl)amine
- 1-AMINO-3-PHENOXY-PROPAN-2-OL
- 3-phenoxy-1-propanamine
- 3-METHOXY-BENZENE-1,2-DIAMINE
- 3-(ISOPROPYLAMINO)-1,2-PROPANEDIOL
- (+/-)-CGP-12177 HYDROCHLORIDE
- AKOS BBS-00007965
- N-(3-METHOXYPHENYL)UREA
- 3-ETHOXYBENZENE-1,2-DIAMINE
- O-METHOXYPHENYLUREA
- 1-METHYLAMINO-3-PHENOXY-PROPAN-2-OL