2-Hydroxybenzimidazole
2-Hydroxybenzimidazole Basic information
- Product Name:
- 2-Hydroxybenzimidazole
- Synonyms:
-
- o-phenylene urea
- RARECHEM AQ NN 0099
- TIMTEC-BB SBB004209
- TIMTEC-BB SBB000067
- 2-Hydroxybenzimidazole,2(1H)-Benzimidazolone (1H-Benzimidazol-2-ol)
- 2-hydroxy and iMidazole
- 2H-Benzimidazol-2-one, 1,3-dihydro-
- o-Benzimidazolone
- CAS:
- 615-16-7
- MF:
- C7H6N2O
- MW:
- 134.14
- EINECS:
- 210-412-4
- Product Categories:
-
- Imidazoles, Pyrroles, Pyrazoles, Pyrrolidines
- Imidazol&Benzimidazole
- BENZIMIDAZOLE
- PHARMACEUTICAL INTERMEDIATES
- Benzimidazole Series
- pharmaceutical
- Benzimidazoles
- Bioactive Small Molecules
- Building Blocks
- Cell Biology
- Chemical Synthesis
- H
- Heterocyclic Building Blocks
- Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
- API intermediates
- Intermediates & Fine Chemicals
- Metabolites & Impurities
- Pharmaceuticals
- Mol File:
- 615-16-7.mol
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2-Hydroxybenzimidazole Chemical Properties
- Melting point:
- >300 °C (lit.)
- Boiling point:
- 247.23°C (rough estimate)
- Density
- 1.2296 (rough estimate)
- refractive index
- 1.5880 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- 0.543g/l
- form
- Crystalline Powder
- pka
- 11.95±0.10(Predicted)
- color
- Off-white to pale brown
- Water Solubility
- insoluble
- BRN
- 119866
- LogP
- 1.17 at 23℃ and pH6.2-6.4
- CAS DataBase Reference
- 615-16-7(CAS DataBase Reference)
- NIST Chemistry Reference
- 2H-Benzimidazol-2-one, 1,3-dihydro-(615-16-7)
- EPA Substance Registry System
- 2H-Benzimidazol-2-one, 1,3-dihydro- (615-16-7)
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Safety Information
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 22-24/25-37/39
- WGK Germany
- 1
- RTECS
- DE1625000
- Hazard Note
- Irritant
- TSCA
- Yes
- HS Code
- 29339990
- Toxicity
- LD50 scu-mus: 620 mg/kg ARZNAD 8,42,58
MSDS
- Language:English Provider:2-Hydroxybenzimidazole
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
- Language:English Provider:ALFA
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2-Hydroxybenzimidazole Usage And Synthesis
Chemical Properties
off-white to pale brown crystalline powder
Uses
2-Hydroxybenzimidazole (Lansoprazole EP Impurity D(Rabeprazole EP Impurity K)) is a metabolite of the neuroleptic Droperidol (D679500).
Uses
A metabolite of the neuroleptic Droperidol (D679500).
Synthesis Reference(s)
The Journal of Organic Chemistry, 33, p. 2543, 1968 DOI: 10.1021/jo01270a093
Synthesis, p. 322, 1991 DOI: 10.1055/s-1991-26457
Tetrahedron Letters, 22, p. 2431, 1981 DOI: 10.1016/S0040-4039(01)92925-9
Safety Profile
Moderately toxic by subcutaneous route. When heated to decomposition it emits toxic vapors of NOx.
2-HydroxybenzimidazoleSupplier
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- sales@intatrade.de
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2-Hydroxybenzimidazole(615-16-7)Related Product Information
- 10-Hydroxycamptothecin
- 2-Methylbenzimidazole
- 2-Phenylbenzimidazole
- 2-Aminobenzimidazole
- Hydroxy silicone oil
- benzimidazol-2-one
- Phenformin
- 2-Chlorobenzimidazole
- Urea
- Benzimidazole
- 2-Mercaptobenzoxazole
- 2-Hydroxymethyl-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine hydrochloride
- N-[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]Methyl Lansoprazole Sulfide
- R-(+)-Lansoprazole
- Dexlansoprazole related impurities 1
- Dexlansoprazole impurity 10027-0322
- Dexlansoprazole Intermediate Impurity 1
- NA