Basic information Safety Supplier Related

2-Hydroxybenzimidazole

Basic information Safety Supplier Related

2-Hydroxybenzimidazole Basic information

Product Name:
2-Hydroxybenzimidazole
Synonyms:
  • o-phenylene urea
  • RARECHEM AQ NN 0099
  • TIMTEC-BB SBB004209
  • TIMTEC-BB SBB000067
  • 2-Hydroxybenzimidazole,2(1H)-Benzimidazolone (1H-Benzimidazol-2-ol)
  • 2-hydroxy and iMidazole
  • 2H-Benzimidazol-2-one, 1,3-dihydro-
  • o-Benzimidazolone
CAS:
615-16-7
MF:
C7H6N2O
MW:
134.14
EINECS:
210-412-4
Product Categories:
  • Imidazoles, Pyrroles, Pyrazoles, Pyrrolidines
  • Imidazol&Benzimidazole
  • BENZIMIDAZOLE
  • PHARMACEUTICAL INTERMEDIATES
  • Benzimidazole Series
  • pharmaceutical
  • Benzimidazoles
  • Bioactive Small Molecules
  • Building Blocks
  • Cell Biology
  • Chemical Synthesis
  • H
  • Heterocyclic Building Blocks
  • Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
  • API intermediates
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
Mol File:
615-16-7.mol
More
Less

2-Hydroxybenzimidazole Chemical Properties

Melting point:
>300 °C (lit.)
Boiling point:
247.23°C (rough estimate)
Density 
1.2296 (rough estimate)
refractive index 
1.5880 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
0.543g/l
form 
Crystalline Powder
pka
11.95±0.10(Predicted)
color 
Off-white to pale brown
Water Solubility 
insoluble
BRN 
119866
LogP
1.17 at 23℃ and pH6.2-6.4
CAS DataBase Reference
615-16-7(CAS DataBase Reference)
NIST Chemistry Reference
2H-Benzimidazol-2-one, 1,3-dihydro-(615-16-7)
EPA Substance Registry System
2H-Benzimidazol-2-one, 1,3-dihydro- (615-16-7)
More
Less

Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-37/39
WGK Germany 
1
RTECS 
DE1625000
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29339990
Toxicity
LD50 scu-mus: 620 mg/kg ARZNAD 8,42,58

MSDS

More
Less

2-Hydroxybenzimidazole Usage And Synthesis

Chemical Properties

off-white to pale brown crystalline powder

Uses

2-Hydroxybenzimidazole (Lansoprazole EP Impurity D(Rabeprazole EP Impurity K)) is a metabolite of the neuroleptic Droperidol (D679500).

Uses

A metabolite of the neuroleptic Droperidol (D679500).

Synthesis Reference(s)

The Journal of Organic Chemistry, 33, p. 2543, 1968 DOI: 10.1021/jo01270a093
Synthesis, p. 322, 1991 DOI: 10.1055/s-1991-26457
Tetrahedron Letters, 22, p. 2431, 1981 DOI: 10.1016/S0040-4039(01)92925-9

Safety Profile

Moderately toxic by subcutaneous route. When heated to decomposition it emits toxic vapors of NOx.

2-HydroxybenzimidazoleSupplier

Nanjing Yiyuan Gold
Tel
18061915908
Email
945992976@qq.com
Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Email
sales@boylechem.com
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Email
jkinfo@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Email
market03@meryer.com
INTATRADE GmbH
Tel
+49 3493/605464
Email
sales@intatrade.de