Basic information Safety Supplier Related

1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-Methoxy-2-Methyl-, ethyl ester

Basic information Safety Supplier Related

1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-Methoxy-2-Methyl-, ethyl ester Basic information

Product Name:
1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-Methoxy-2-Methyl-, ethyl ester
Synonyms:
  • 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-Methoxy-2-Methyl-, ethyl ester
  • Indometacin EP Impurity I
  • Indomethacin Impurity I
  • Indomethacin Impurity 9(Indomethacin EP Impurity I)
  • Indomethacin impurity 8/Indomethacin EP impurity I/ethyl 2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetate
  • Indomethacin Imp I
  • Indomethacin EP Impurity I
  • ethyl 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetate
CAS:
16401-99-3
MF:
C21H20ClNO4
MW:
385.84
Mol File:
16401-99-3.mol
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1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-Methoxy-2-Methyl-, ethyl ester Chemical Properties

Melting point:
95-96 °C
Boiling point:
475.3±45.0 °C(Predicted)
Density 
1.24±0.1 g/cm3(Predicted)
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1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-Methoxy-2-Methyl-, ethyl ester Usage And Synthesis

Uses

Indomethacin Ethyl Ester (Indomethacin EP Impurity I) is the ethyl ester of the nonsteroidal anti-inflammatory drug Indomethacin (I641000). Indomethacin Ethyl Ester is a selective COX-2 inhibitor and is used (along with Indomethacin) as loaded nanocapsules as anticancer treatment showing a decrease in glioma cell proliferation.

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