ChemicalBook > Product Catalog > Biochemical Engineering > Biochemical Reagents > Agonist Inhibitors > BVT-14225
BVT-14225
BVT-14225 Basic information
- Product Name:
- BVT-14225
- Synonyms:
-
- BVT-14225
- 4-Thiazoleacetamide,2-[[(3-chloro-2-methylphenyl)sulfonyl]amino]-N,N-diethyl-
- BVT14225;BVT 14225
- BVT-14225, >98%
- 2-(2-(3-Chloro-2-methylphenylsulfonamido)thiazol-4-yl)-n,n-diethylacetamide
- inhibit,Inhibitor,BVT-14225,BVT14225
- 2-[2-(3-chloro-2-methylbenzenesulfonamido)-1,3-thiazol-4-yl]-N,N-diethylacetamide
- BVT-14225, 10 mM in DMSO
- CAS:
- 376638-65-2
- MF:
- C16H20ClN3O3S2
- MW:
- 401.93
- Mol File:
- 376638-65-2.mol
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BVT-14225 Chemical Properties
- Boiling point:
- 586.5±60.0 °C(Predicted)
- Density
- 1.373±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO : ≥ 27 mg/mL (67.18 mM)
- pka
- 6.34±0.10(Predicted)
- form
- Solid
- color
- White to off-white
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BVT-14225 Usage And Synthesis
Uses
BVT-14225 is a selective 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with an IC50 of 52 nM.
References
[1] Barf T, et al. Arylsulfonamidothiazoles as a new class of potential antidiabetic drugs. Discovery of potent and selective inhibitors of the 11beta-hydroxysteroid dehydrogenase type 1. J Med Chem. 2002 Aug 29;45(18):3813-5. DOI:10.1021/jm025530f
[2] Vicker N, et al. Novel non-steroidal inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1. J Steroid Biochem Mol Biol. 2007 May;104(3-5):123-9. DOI:10.1016/j.jsbmb.2007.03.023
BVT-14225Supplier
Shanghai Boyle Chemical Co., Ltd.
- Tel
- sales@boylechem.com
Nanjing Chemlin Chemical Co., Ltd
- Tel
- 025-83697070 13913916777;
- info@chemlin.com.cn
BOC Sciences
- Tel
- 1-631-485-4226; 16314854226
- info@bocsci.com
Shanghai JiYi Biotechnology Co. Ltd.
- Tel
- 13621943973
- sales@shjiyipharmatech.com
Shanghai Lollane Biological Technology Co.,Ltd.
- Tel
- 021-52996696，15000506266 15000506266