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135270-13-2

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135270-13-2 Basic information

Product Name:
135270-13-2
Synonyms:
  • 1-(((2R,3R)-2-(2,4-difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole
  • Efinaconazole Related Impurity 6
  • 1-[[(2R,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-oxiranyl]methyl]-1H-1,2,4-triazole
  • Efinaconazole Epoxy Impurity
  • Efinaconazole Impurity 2
  • Efinaconazole Related Impurity
  • 1H-1,2,4-Triazole, 1-[[(2R,3R)-2-(2,4-difluorophenyl)-3-methyl-2-oxiranyl]methyl]-
  • 1-(((2R,3R)-2-(2,4-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole (Efinaconazole Impurity)
CAS:
135270-13-2
MF:
C12H11F2N3O
MW:
251.23
Mol File:
135270-13-2.mol
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135270-13-2 Chemical Properties

Boiling point:
371.6±52.0 °C(Predicted)
Density 
1.41±0.1 g/cm3(Predicted)
pka
2.75±0.10(Predicted)
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135270-13-2 Usage And Synthesis

Uses

(2R,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane is a useful synthetic intermediate in the synthesis of (2R,3S)-Efinaconazole (E435080); the 2R,3S-enantiomer of Efinaconazole (E435070) which is a topical antifungal for onychomycosis.

135270-13-2Supplier

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