(SAR1,ILE4,8)-ANGIOTENSIN II Chemical Properties

Density 

1.34±0.1 g/cm3(Predicted)

form 

Solid

pka

3.72±0.22(Predicted)

color 

White to off-white

Sequence

{Sar}-Arg-Val-Ile-Ile-His-Pro-Ile

(SAR1,ILE4,8)-ANGIOTENSIN II Usage And Synthesis

Uses

(Sar1,Ile4,8)-Angiotensin II is a functionally selective angiotensin II type 1 receptor (AT1R) agonist. (Sar1,Ile4,8)-Angiotensin II potentiates insulin-stimulated insulin receptor (IR) signaling and glycogen synthesis. (Sar1,Ile4,8)-Angiotensin II potentiates insulin-stimulated phosphorylation of Akt and GSK3α/β[1].

IC 50

Angiotensin II Type 1

References

[1] Sanni SJ, et al. [Sar1, Ile4, Ile8]-angiotensin II Potentiates Insulin Receptor Signalling and Glycogen Synthesis in Hepatocytes. Basic Clin Pharmacol Toxicol. 2018 May;122(5):460-469. DOI:10.1111/bcpt.12937

(SAR1,ILE4,8)-ANGIOTENSIN II(185461-45-4)Related Product Information

• BRADYKININ (1-6)
• Angiogenin (108-122) TFA
• ANGIOTENSIN I/II (1-5)
• ABZ-GLY-4-NITRO-PHE-PRO-OH
• ANGIOTENSIN I/II (3-7)
• (DES-ASP1,ILE8)-ANGIOTENSIN II
• ASP-ARG-VAL-TYR
• ANGIOTENSIN I/II (1-6)
• Angiotensin acetate
• H-MET-LYS-ARG-SER-ARG-GLY-PRO-SER-PRO-ARG-ARG-OH
• ANGIOTENSIN I/II (4-8)
• ANGIOTENSIN II, HUMAN
• H-ARG-PRO-PRO-GLY-PHE-SER-PRO-OH ACETATE SALT
• SAR-ARG-VAL-TYR-ILE-HIS-PRO-PHE
• (SAR1,GLY8)-ANGIOTENSIN II
• (SAR1,THR8)-ANGIOTENSIN II
• SARALASIN
• H2N-DRVYIHP-AMIDE