H-LEU-LEU-OH Chemical Properties

Melting point:

270-272℃ (decomposition)

Boiling point:

432.7±30.0 °C(Predicted)

Density 

1.051±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

solubility 

Methanol (Slightly, Heated), Water (Slightly, Sonicated)

form 

Solid

pka

3.16±0.10(Predicted)

color 

White to Off-White

InChI

InChI=1S/C12H24N2O3/c1-7(2)5-9(13)11(15)14-10(12(16)17)6-8(3)4/h7-10H,5-6,13H2,1-4H3,(H,14,15)(H,16,17)/t9-,10-/m0/s1

InChIKey

LCPYQJIKPJDLLB-UWVGGRQHSA-N

SMILES

C(O)(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)N

Safety Information

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

H-LEU-LEU-OH Usage And Synthesis

Chemical Properties

White powder

Uses

Leu-Leu-OH (L-Leucyl-L-leucine), a Leu derivative, is a neutral dipeptide that can be used to study the functionality of dileucine motifs[1].

Definition

ChEBI: A dipeptide formed from two L-leucine residues.

Biological Activity

Leucylleucine (Leu-Leu) may be used to study the functionality of dileucine motifs such as the motif responsible for internalization and targeting of vesicular acetylcholine transporter and clathrin adaptors AP-1 and AP-2.

References

[1] Matthews DM, et al. Uptake of L-leucyl-L-leucine and glycylsarcosine by hamster jejunum in vitro. Clin Sci (Lond). 1983 Aug;65(2):177-84. DOI:10.1042/cs0650177

H-LEU-LEU-OH(3303-31-9)Related Product Information

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