Tofacitinib Impurity L Chemical Properties

Melting point:

>113°C (dec.)

storage temp. 

-20°C Freezer, Under inert atmosphere

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

color 

Off-White to Pale Orange

Tofacitinib Impurity L Usage And Synthesis

Uses

Tofacitinib impurity L is an impurity of Tofacitinib (T528000), an enantiopure stereoisomer of the drug, Janus kinase 3(Jak3) inhibitor (CP-690,550) that has been found to inhibit selected members of the STE7 and STE20 subfamily of kinases.