methyl2-(chloromethyl)-4-phenoxybenzoate Chemical Properties

Boiling point:

407.9±45.0 °C(Predicted)

Density 

1.226±0.06 g/cm3(Predicted)

InChI

InChI=1S/C15H13ClO3/c1-18-15(17)14-8-7-13(9-11(14)10-16)19-12-5-3-2-4-6-12/h2-9H,10H2,1H3

InChIKey

YDISGIKGRQZDOU-UHFFFAOYSA-N

SMILES

C(OC)(=O)C1=CC=C(OC2=CC=CC=C2)C=C1CCl

methyl2-(chloromethyl)-4-phenoxybenzoate Usage And Synthesis

Uses

methyl2-(chloromethyl)-4-phenoxybenzoate is a pharmaceutical intermediate compound used in the preparation of roxadustat, a hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor used in the treatment of symptomatic conditions associated with chronic kidney disease (CKD).

methyl2-(chloromethyl)-4-phenoxybenzoate(1455091-04-9)Related Product Information

• Roxadustat
• methyl 4-hydroxy-6-phenoxyisoquinoline-3-carboxylate
• methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate
• 1(3H)-Isobenzofuranone, 5-phenoxy-
• Roxadustat Impurity
• 2-{[(methoxycarbonylmethyl)(toluene-4-sulfonyl)amino]methyl}-4-phenoxybenzoic acid methyl ester
• methyl 1-chloro-4-hydroxy-7-phenoxyisoquinoline-3-carboxylate