Boc-aminooxy-PEG3-Propargyl Chemical Properties

Density 

1.078±0.06 g/cm3(Predicted)

Boc-aminooxy-PEG3-Propargyl Usage And Synthesis

Description

t-Boc-aminooxy-PEG3-propargyl is a click reagent with a propargyl group and t-Boc-aminooxy group. The propargyl group can react with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry. T-Boc-aminooxy group can be free up under mild acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

N-Boc-aminoxy-PEG3-propargyl is a crosslinker containing a propargyl group and a t-Boc-aminooxy group. N-Boc-aminoxy-PEG3-propargyl can be used in the synthesis of ADC[1].

References

[1] Sano K, et al. Short PEG-linkers improve the performance of targeted, activatable monoclonal antibody-indocyanine green optical imaging probes. Bioconjug Chem. 2013 May 15;24(5):811-6. DOI:10.1021/bc400050k

Boc-aminooxy-PEG3-Propargyl(1951439-46-5)Related Product Information

• t-Boc-Aminooxy-PEG4-CH2CO2H
• Boc-Aminooxy-PEG3-acid
• t-Boc-Aminooxy-PEG3-S-Ac
• Boc-Aminooxy-PEG3-bromide
• Boc-Aminooxy-PEG3-thiol
• t-Boc-Aminooxy-PEG3-oxyamine