A[5']P5[5']A AMMONIUM SALT Chemical Properties

storage temp. 

-20°C

solubility 

H₂O: 50 mg/mL

form 

powder

color 

white with faint yellow cast

Safety Information

WGK Germany 

3

F 

10-21

MSDS

• Language:English Provider:SigmaAldrich

A[5']P5[5']A AMMONIUM SALT Usage And Synthesis

Biochem/physiol Actions

A diadenosine polyphosphate stored in secretory granules of thrombocytes, chromaffin and neuronal cells. After release into the extracellular space, it affects a variety of biological activities in a wide range of target tissues. In the nervous system it acts through various purinergic receptors. It also activates 5′-nucleotidase and inhibits adenosine kinase activity in vitro. Ap5A is metabolized by soluble enzymes in the blood plasma and by membrane-bound ectoenzymes of a number of cell types including endothelial and smooth muscle cells. In heart, it increases contractile force and action potential duration, and shows an anti-β-adrenergic effect.

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