YU238259 CAS#: 1943733-16-1

Product Name:

YU238259

Synonyms:

YU238259
YU-238259;YU 238259
Benzamide, N-[2-(5-chloro-2-pyridinyl)ethyl]-4-[[[(4-methoxyphenyl)sulfonyl]amino]methyl]-
N-(2-(5-Chloropyridin-2-yl)ethyl)-4-(((4-methoxyphenyl)sulfonamido)methyl)benzamide
inhibit,Inhibitor,DNA-dependent protein kinase,DNA-PK,YU 238259,YU-238259,YU238259
YU238259, 10 mM in DMSO

CAS:

1943733-16-1

MF:

C22H22ClN3O4S

MW:

459.95

Mol File:

1943733-16-1.mol

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Density: 1.323±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
solubility: DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:10): 0.1 mg/ml
form: A crystalline solid
pka: 11.46±0.50(Predicted)
color: White to off-white

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YU 238259 is an anticancer agent that inhibits DNA damage repair. It also sensitizes tumors cells to radiation.

YU238259 (3 mg/kg, i.p.) inhibits the growth of BRCA2-deficient tumor xenografts in nude mice^[1].

Shanghai Boyle Chemical Co., Ltd.

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

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Shanghai YuanYe Biotechnology Co., Ltd.

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YU238259