alpha,2-Dimethyl-5-nitro-1H-imidazole-1-ethanol Chemical Properties

Melting point:

76°C

Boiling point:

396.1±22.0 °C(Predicted)

Density 

1.39±0.1 g/cm3(Predicted)

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Chloroform (Sparingly), Methanol (Sparingly)

pka

14.50±0.20(Predicted)

form 

Solid

color 

White to Light Yellow

λmax

319nm(H2O)(lit.)

Merck 

14,8419

CAS DataBase Reference

3366-95-8(CAS DataBase Reference)

Safety Information

HS Code 

2933.29.2000

MSDS

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alpha,2-Dimethyl-5-nitro-1H-imidazole-1-ethanol Usage And Synthesis

Chemical Properties

Crystalline Solid

Uses

antiameobic, antitrichomonas

Uses

Analog of Metronidazole. Antiamebic. Antiprotozoal (Trichomonas).

Definition

ChEBI: Secnidazole is a C-nitro compound that is 5-nitroimidazole in which the hydrogens at positions 1 and 2 are replaced by 2-hydroxypropyl and methyl groups, respectively. It has a role as an epitope. It is a C-nitro compound, a member of imidazoles and a secondary alcohol.

Pharmaceutical Applications

A 5-nitroimidazole with properties similar to those of metronidazole. It is rapidly absorbed after oral administration and is distinguished by having the longest plasma half-life (18 h) of clinically used nitroimidazole drugs. It is used in the treatment of intestinal amebiasis, giardiasis, trichomoniasis and bacterial vaginosis.

alpha,2-Dimethyl-5-nitro-1H-imidazole-1-ethanol(3366-95-8)Related Product Information

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