β-Lactamase inhibitors Aminoglycosides drugs Macrolides Peptides drug Polyenes drug Rifamycin drugs Lincosamides Drugs Other β- lactam Drugs Other antibiotic Drugs Penicillins drugs Tetracycline drugs Cephalosporins Drugs Amphenicols Drugs Agricultural antibiotics
ChemicalBook >   Product Catalog >  API >  Antibiotics

Antibiotics

β-Lactamase inhibitors Aminoglycosides drugs Macrolides Peptides drug Polyenes drug Rifamycin drugs Lincosamides Drugs Other β- lactam Drugs Other antibiotic Drugs Penicillins drugs Tetracycline drugs Cephalosporins Drugs Amphenicols Drugs Agricultural antibiotics
More
Less

The first discovered antibiotic is penicillin. It was developed during World War II, due to the demand for effective anti-infective agent. In fact, people had realized the effects of these substances at as early as 1870s when people had observed the antagonistic phenomena between microorganisms. However, it was not until 1942 when S. A. Waksman observed these activities that people began to adopt the term of antibiotic. Although in 1928, A. Fleming had discovered the penicillin, however, people didn’t realize the importance of it due to that people hadn’t yet confirmed that this kind of natural-derived anti-microbial agents is capable of taking effect against systemic infection in humans and animals. It was not until the war pressure stimulated the research to combat infectious diseases agent, H. W. Florey and his colleagues E. B. Chain had extracted the refined products of penicillin and successfully demonstrated the effectiveness of penicillin treatment. In 1943, Waxman found a second antibiotic - streptomycin, and then proceeded to observe the antimicrobial effects of isolated bacitracin, neomycin, polymyxin, chloramphenicol, chlortetracycline, oxytetracycline and some other antibiotics, the importance of all antibiotics has shown up. With the success of the antibiotics in the chemical treatment, people have also further found that they also had wide applications in plant protection, animal husbandry, food preservation and other aspects.

Antibiotics generally refer to a class of substances produced during the life process of bacteria, fungi and other microbes with anti-pathogen properties. It is also important drugs for controlling the human and livestock diseases, anti-tumor as well as treatment of plant pest diseases. Antibiotic is a kind of secondary metabolites of microorganisms with small amount and low concentrations usage being able inhibit and kill another kind of microorganism. There are also some antibiotics having anti-tumor or other kinds of effect. Since the application of penicillin in medical treatment in the beginning of 1940, it had discovered and invented of several thousands of species of antibiotics, however there is no more than 100 kinds having been used in clinical application. These antibiotics are extracted from a microbial culture medium or manufactured through semi-synthesis or synthesis. Antibiotics, according to their origin and effect, are generally divided into penicillins, cephalosporins, aminoglycosides, tetracyclines, chloramphenicol, and macrolide, anti-fungal and anti-tumor. There are divided to broad spectrum and narrow spectrum based on the antimicrobial spectrum range.

The antibacterial mechanism and the role of various antibiotics also vary. For example, penicillin and bacitracin can hinder the bacterial cell wall synthesis; peptide antibiotics can destroy the bacterial plasma membrane; chloramphenicol and streptomycin can interfere with the protein synthesis or nucleic acid synthesis. Some antibiotics have small spectrum; for example, penicillin is only effective against gram-positive bacteria, and thus being called narrow spectrum antibiotics. Some antibiotics have broader spectrum for example tetracycline has inhibitory effect on most bacteria and is called broad-spectrum antibiotics.

There are about 100 kinds of antibiotics that have been get applied. For example, penicillin, streptomycin, and gentamicin have been widely used for medical treatment. In agriculture kasugamycin and Jinggangmycin have been widely used in the prevention and treatment of rice germs. Blasticidin has been used for the control of rice blast; GA is used for promoting the growth of plants and so on. However, the use of antibiotics be according to the condition used and should be avoided of using indiscriminately. Some antibiotics can produce some side effects for example continuous application of streptomycin and gentamicin can cause deafness while overdose of chloramphenicol can cause leukopenia. Some people are allergic to certain antibiotics with fatal effect in serious conditions. Therefore, “skin test” is needed for some antibiotics (such as penicillin) before use.

Rational application of antibiotics is the key issue during antibiotic application. Blindly misuse of antibiotics, especially long-term use of broad-spectrum antibiotics, will not only lead to resistant strains, and many antibiotics have side effects that can’t be ignored. They can even cause severe consequence of “secondary infection” due to the destruction of the body's normal flora. Therefore, we must strictly apply them in accordance with the prescription.

Agricultural Antibiotics: Since in 1950s when people had found that blasticidin S is effective in treating rice blast, it has developed into a fairly large class of antibiotics to date. There are a lot of antibiotics of anti-bacterial and anti-fungal for treating crop diseases such as kasugamycin (kasugamycin), Jinggangmycin (i.e. validamycin), polyoxin and actidione and so on. Some pesticides such as aphid-killing agents such as tetranactin and piercicidin have excellent control effect on some crop pest diseases. Some antibiotics can also significantly promote the growth of plants such as GA (gibberellin) and so on.

Click on the specific product, view the latest prices of the products, information, serving information

Structure:
Chemical Name:
6-Aminopenicillanic acid
CAS:
551-16-6
MF:
C8H12N2O3S
Structure:
Chemical Name:
Oseltamivir phosphate
CAS:
204255-11-8
MF:
C16H31N2O8P
Structure:
Chemical Name:
Bismuththiol
CAS:
1072-71-5
MF:
C2H2N2S3
Structure:
Chemical Name:
2-Aminothiazol-4-acetic acid
CAS:
29676-71-9
MF:
C5H6N2O2S
Structure:
Chemical Name:
Geldanamycin
CAS:
30562-34-6
MF:
C29H40N2O9
Structure:
Chemical Name:
Posaconazole
CAS:
171228-49-2
MF:
C37H42F2N8O4
Structure:
Chemical Name:
Hygromycin B
CAS:
31282-04-9
MF:
C20H37N3O13
Structure:
Chemical Name:
Oxacillin sodium monohydrate
CAS:
7240-38-2
MF:
C19H18N3NaO5S
Structure:
Chemical Name:
Cefodizime sodium
CAS:
86329-79-5
MF:
C20H18N6Na2O7S4
Structure:
Chemical Name:
Rifamycin O
CAS:
14487-05-9
MF:
C39H47NO14
Structure:
Chemical Name:
Erythromycin
CAS:
114-07-8
MF:
C37H67NO13
Structure:
Chemical Name:
Sulfapyridine
CAS:
144-83-2
MF:
C11H11N3O2S
Structure:
Chemical Name:
Amorolfine hydrochloride
CAS:
78613-38-4
MF:
C21H36ClNO
Structure:
Chemical Name:
Enrofloxacin
CAS:
93106-60-6
MF:
C19H22FN3O3
Structure:
Chemical Name:
1,1,1,2-Tetrafluoroethane
CAS:
811-97-2
MF:
C2H2F4
Structure:
Chemical Name:
7-Aminocephalosporanic acid
CAS:
957-68-6
MF:
C10H12N2O5S
Structure:
Chemical Name:
Colistin sulfate
CAS:
1264-72-8
MF:
2(C52H98N16O13).5(H2SO4)
Structure:
Chemical Name:
Sulfadoxine
CAS:
2447-57-6
MF:
C12H14N4O4S
Structure:
Chemical Name:
FLORFENICOL
CAS:
76639-94-6
MF:
C12H14Cl2FNO4S
Structure:
Chemical Name:
Cefozopran
CAS:
113359-04-9
MF:
C19H17N9O5S2
Structure:
Chemical Name:
Ciprofloxacin hydrochloride hydrate
CAS:
86393-32-0
MF:
C17H21ClFN3O4
Structure:
Chemical Name:
Darunavir
CAS:
206361-99-1
MF:
C27H37N3O7S
Structure:
Chemical Name:
Lincomycin hydrochloride monohydrate
CAS:
7179-49-9
MF:
C18H37ClN2O7S
Structure:
Chemical Name:
Liranaftate
CAS:
88678-31-3
MF:
C18H20N2O2S
Structure:
Chemical Name:
Quinine hydrochloride dihydrate
CAS:
6119-47-7
MF:
C20H29ClN2O4
Structure:
Chemical Name:
THIOSTREPTON
CAS:
1393-48-2
MF:
C72H85N19O18S5
Structure:
Chemical Name:
Rifaximin
CAS:
80621-81-4
MF:
C43H51N3O11
Structure:
Chemical Name:
Cinchonidine
CAS:
485-71-2
MF:
C19H22N2O
Structure:
Chemical Name:
Ampicillin
CAS:
7177-48-2
MF:
C16H25N3O7S
Structure:
Chemical Name:
CLINDAMYCIN HYDROCHLORIDE
CAS:
58207-19-5
MF:
C18H34Cl2N2O5S
Structure:
Chemical Name:
Cemandil sodium salt
CAS:
42540-40-9
MF:
C19H17N6NaO6S2
Structure:
Chemical Name:
Ceftiofur hydrochloride
CAS:
103980-44-5
MF:
C19H18ClN5O7S3
Structure:
Chemical Name:
7-Amino-3-vinyl-3-cephem-4-carboxylic acid diphenylmethyl ester monohydrochloride
CAS:
79349-67-0
MF:
C22H21ClN2O3S
Structure:
Chemical Name:
Tigecycline
CAS:
220620-09-7
MF:
C29H39N5O8
Structure:
Chemical Name:
5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine
CAS:
6981-18-6
MF:
C14H18N4O2
Structure:
Chemical Name:
GCLH
CAS:
64308-63-0
MF:
C29H25ClN2O4S
Structure:
Chemical Name:
Ceftiofur sodium
CAS:
104010-37-9
MF:
C19H18N5NaO7S3
Structure:
Chemical Name:
Tilmicosin
CAS:
108050-54-0
MF:
C46H80N2O13
Structure:
Chemical Name:
Amoxicillin trihydrate
CAS:
61336-70-7
MF:
C16H25N3O8S
Structure:
Chemical Name:
SULFACHLOROPYRIDAZINE
CAS:
80-32-0
MF:
C10H9ClN4O2S
Structure:
Chemical Name:
CEFATHIAMIDINE
CAS:
33075-00-2
MF:
C19H28N4O6S2
Structure:
Chemical Name:
Tobramycin
CAS:
32986-56-4
MF:
C18H37N5O9
Structure:
Chemical Name:
OLIGOMYCIN
CAS:
1404-19-9
MF:
C135H220O33
Structure:
Chemical Name:
VALINOMYCIN
CAS:
2001-95-8
MF:
C54H90N6O18
Structure:
Chemical Name:
Valienamine
CAS:
38231-86-6
MF:
C7H13NO4
Structure:
Chemical Name:
WORTMANNIN
CAS:
19545-26-7
MF:
C23H24O8
Structure:
Chemical Name:
Estradiol
CAS:
57-91-0
MF:
C18H24O2
Structure:
Chemical Name:
CORTICOSTERONE
CAS:
50-22-6
MF:
C21H30O4
Structure:
Chemical Name:
7-Amino-3-chloro cephalosporanic acid
CAS:
53994-69-7
MF:
C7H7ClN2O3S
Structure:
Chemical Name:
Clindamycin phosphate
CAS:
24729-96-2
MF:
C18H34ClN2O8PS
Structure:
Chemical Name:
Oxolinic acid
CAS:
14698-29-4
MF:
C13H11NO5
Structure:
Chemical Name:
TRICHOSTATIN A
CAS:
58880-19-6
MF:
C17H22N2O3
Structure:
Chemical Name:
Polymyxin B sulfate
CAS:
1405-20-5
MF:
C56H100N16O17S
Structure:
Chemical Name:
Imipenem
CAS:
74431-23-5
MF:
C10H12N2O3S
Structure:
Chemical Name:
Rosiglitazone maleate
CAS:
155141-29-0
MF:
C22H23N3O7S
Structure:
Chemical Name:
ZANAMIVIR HYDRATE
CAS:
139110-80-8
MF:
C12H20N4O7
Structure:
Chemical Name:
Tiamulin fumarate
CAS:
55297-96-6
MF:
C32H51NO8S
Structure:
Chemical Name:
Side chain for meropenem
CAS:
96034-64-9
MF:
C15H19N3O5S
Chemical Name:
Chondroitin sulfate A sodium salt
CAS:
39455-18-0
MF:
(C14H19NO14SNa2)n
Structure:
Chemical Name:
(Z)-2-Amino-alpha-[1-(tert-butoxycarbonyl)]-1-methylethoxyimino-4-thiazolacetic acid
CAS:
86299-47-0
MF:
C13H19N3O5S
Structure:
Chemical Name:
Phosphomycin calcium salt
CAS:
26016-98-8
MF:
C3H5CaO4P
Structure:
Chemical Name:
TAEM
CAS:
158183-05-2
MF:
C20H22N4O4S3
Structure:
Chemical Name:
Atazanavir
CAS:
198904-31-3
MF:
C38H52N6O7
Structure:
Chemical Name:
Doripenem hydrate
CAS:
364622-82-2
MF:
C15H26N4O7S2
Structure:
Chemical Name:
Ciclopirox ethanolamine
CAS:
41621-49-2
MF:
C14H24N2O3
Structure:
Chemical Name:
Rifabutin
CAS:
72559-06-9
MF:
C46H62N4O11
Structure:
Chemical Name:
Erythromycin thiocyanate
CAS:
7704-67-8
MF:
C38H68N2O13S
Structure:
Chemical Name:
Rifamycin S
CAS:
13553-79-2
MF:
C37H45NO12
Structure:
Chemical Name:
Cefaclor monohydrate
CAS:
70356-03-5
MF:
C15H16ClN3O5S
Structure:
Chemical Name:
2-Mercaptobenzothiazolyl-(Z)-(2-aminothiazol-4-yl)-2-(tert-butoxycarbonyl) isopropoxyiminoacetate
CAS:
89604-92-2
MF:
C20H22N4O4S3
Structure:
Chemical Name:
Faropenem sodium hemipentahydrate
CAS:
106560-14-9
MF:
C12H15NO5S
Structure:
Chemical Name:
Teicoplanin
CAS:
61036-62-2
MF:
C78H77Cl2N8O32R
Structure:
Chemical Name:
Dirithromycin
CAS:
62013-04-1
MF:
C42H78N2O14
Structure:
Chemical Name:
7-Amino-3-cephem-4-carboxylic acid
CAS:
36923-17-8
MF:
C7H8N2O3S
Structure:
Chemical Name:
Sulbactam
CAS:
68373-14-8
MF:
C8H11NO5S
Structure:
Chemical Name:
Streptozotocin
CAS:
18883-66-4
MF:
C8H15N3O7
Structure:
Chemical Name:
Telithromycin
CAS:
191114-48-4
MF:
C43H65N5O10
Structure:
Chemical Name:
Doripenem
CAS:
148016-81-3
MF:
C15H24N4O6S2
Structure:
Chemical Name:
Tetracycline hydrochloride
CAS:
64-75-5
MF:
C22H25ClN2O8
Structure:
Chemical Name:
3-[[[(2S,4S)-4-Mercapto-1-(4-nitrobenzyloxy)carbonyl-2-pyrrolidinyl]carbonyl]amino]benzoic acid
CAS:
202467-69-4
MF:
C20H19N3O7S
Structure:
Chemical Name:
BIAPENEM SIDE CHAIN
CAS:
153851-71-9
MF:
C5H8ClN3S
Structure:
Chemical Name:
Tilmicosin phosphate
CAS:
137330-13-3
MF:
C46H83N2O17P
Structure:
Chemical Name:
STAUROSPORINE
CAS:
62996-74-1
MF:
C28H26N4O3
Structure:
Chemical Name:
Kanamycin sulfate
CAS:
25389-94-0
MF:
C18H38N4O15S
Structure:
Chemical Name:
Gentamycin sulfate
CAS:
1405-41-0
MF:
C60H127N15O26S
Structure:
Chemical Name:
Cefprozil hydrate
CAS:
121123-17-9
MF:
C18H21N3O6S
Structure:
Chemical Name:
Cilastatin
CAS:
82009-34-5
MF:
C16H26N2O5S
Structure:
Chemical Name:
Ticarcillin disodium salt
CAS:
4697-14-7
MF:
C15H14N2Na2O6S2
Structure:
Chemical Name:
Ceftriaxone sodium
CAS:
104376-79-6
MF:
C18H16N8Na2O7S3.31/2H2O
Structure:
Chemical Name:
Chloramphenicol
CAS:
56-75-7
MF:
C11H12Cl2N2O5
Structure:
Chemical Name:
Tylosin tartrate
CAS:
74610-55-2
MF:
C49H81NO23
Structure:
Chemical Name:
Atazanavir sulfate
CAS:
229975-97-7
MF:
C38H52N6O7.H2SO4
Structure:
Chemical Name:
Ceftiofur
CAS:
80370-57-6
MF:
C19H17N5O7S3
Structure:
Chemical Name:
Cefeprime dihydrochloride
CAS:
107648-80-6
MF:
C19H25ClN6O5S2
Structure:
Chemical Name:
Dalbavancin
CAS:
171500-79-1
MF:
C88H100Cl2N10O28
Structure:
Chemical Name:
PUROMYCIN DIHYDROCHLORIDE
CAS:
58-58-2
MF:
C22H31Cl2N7O5
Structure:
Chemical Name:
p-Nitrobenzyl-6-(1-hydroxyethyl)-1-azabicyclo(3.2.0)heptane-3,7-dione-2-carboxylate
CAS:
74288-40-7
MF:
C16H16N2O7
Structure:
Chemical Name:
AMPRENAVIR
CAS:
161814-49-9
MF:
C25H35N3O6S
Structure:
Chemical Name:
TUNICAMYCIN
CAS:
11089-65-9
MF:
C37H60N4O16
Structure:
Chemical Name:
Cefoselis sulfate
CAS:
122841-12-7
MF:
C19H24N8O10S3