Basic information Brand Name(s) in US Third-generation cephalosporins Uses Safety Supplier Related
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Ceftiofur sodium

Basic information Brand Name(s) in US Third-generation cephalosporins Uses Safety Supplier Related

Ceftiofur sodium Basic information

Product Name:
Ceftiofur sodium
Synonyms:
  • (6R-(6alpha,7beta(Z))-7-(((2-Amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((2-furanylcarbonyl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt
  • naxcel
  • u-64279e
  • CEFTIOFUR SODIUM
  • ceftiofur sodium salt
  • SODIUM CEFTIOFUR
  • Ceftiofur Sodic
  • 5-Thia-1-azabicyclo4.2.0oct-2-ene-2-carboxylic acid, 7-(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetylamino-3-(2-furanylcarbonyl)thiomethyl-8-oxo-, monosodium salt, (6R,7R)-
CAS:
104010-37-9
MF:
C19H18N5NaO7S3
MW:
547.55
EINECS:
680-655-2
Product Categories:
  • Pharmaceutical intermediate
  • Antibiotics
  • We have in stock now.
  • APIs
  • cephalosporins antibiotics
  • veterinary drugs
Mol File:
104010-37-9.mol
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Ceftiofur sodium Chemical Properties

RTECS 
XI0367360
solubility 
Freely soluble in aqueous solution
InChIKey
RFLHUYUQCKHUKS-JUODUXDSSA-M
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Safety Information

WGK Germany 
3
HS Code 
2941906000
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Ceftiofur sodium Usage And Synthesis

Brand Name(s) in US

Naxcel

Third-generation cephalosporins

Ceftiofur sodium is the sodium salt of ceftiofur, which belongs to the third generation cephalosporin antibiotics, for the first time in 1988 it was listed in the United States. Chemical properties are stabie, appearance is light yellow to white crystalline powder, aqueous solution has a shorter retention time, it should be diluted into a solution before use.
Ceftiofur has a broad antimicrobial spectrum , it has a strong antibacterial activity , it has a strong antibacterial activity against Gram-positive bacteria, Gram-negative bacteria, and some anaerobic bacteria ,its antibacterial activity is similar to or weaker than the first-generation cephalosporins against Gram-positive bacteria , it has a strong antibacterial activity against Gram-negative bacteria such as E. coli, Salmonella, Pasteurella and so on. It is used for a variety of respiratory, urinary tract and other infections caused by sensitive bacteria, especially for the prevention and treatment of early death of chicks caused by E. coli, Salmonella, Pseudomonas aeruginosa, Staphylococcus aureus , E. coli yellow dysentery of 1 piglets and wound infections caused by cutting the umbilical cord, ear numbers, cutting teeth, tails and others,
pleuropneumoniae and bovine bronchial pneumonia caused by Haemophilus and Actinobacillus , generally it does not apply to cows and goats mastitis treatment . Some researchers have done ceftiofur sodium inhibition tests for thousands strains of pathogens isolated by veterinary clinically , the results show that the drug is one of the most active anti-bacterial drugs, it has a strong antibacterial activity against Escherichia coli, p.multocida and p.haemolytica ,Bacillus typhosus, Streptococcus ; it also has a good effect on Pseudomonas aeruginosa, Enterobacter, anaerobic bacteria. It is used for the treatment of respiratory disease of sheep,horses, cattle, pigs (pleuropneumonia),and the treatment of pets, day-old broiler infectious diseases. This product has characteristics such as complete intramuscular absorption and long elimination half-life period .
The above information is edited by the chemicalbook of Tian Ye.

Uses

It belongs to antibiotic medicines for the treatment of swine bacterial respiratory infection

Chemical Properties

White or light yellow crystalline powder

Uses

Antibacterial (veterinary).

Veterinary Drugs and Treatments

Labeled indications for ceftiofur sodium:
In cattle for treatment of bovine respiratory disease (shipping fever, pneumonia) associated with Mannheimia haemolytica, Pasteurella multocida and Histophilus somni. It is also indicated for treatment of acute bovine interdigital necrobacillosis (foot rot, pododermatitis) associated with Fusobacterium necrophorum and Bacteroides melaninogenicus.
In swine for treatment/control of swine bacterial respiratory disease (swine bacterial pneumonia) associated with Actinobacillus (Haemophilus) pleuropneumoniae, Pasteurella multocida, Salmonella choleraesuis and Streptococcus suis.
In sheep/goats for treatment of sheep/caprine respiratory disease (sheep/goat pneumonia) associated with Mannheimia haemolytica and Pasteurella multocida.
In horses for treatment of respiratory infections in horses associated with Streptococcus zooepidemicus. In dogs for the treatment of canine urinary tract infections associated with E. coli and Proteus mirabilis.
In day old chicks/poults for the control of early mortality, associated with E. coli organisms susceptible to ceftiofur.
Ceftiofur sodium has also been used in an extra-label manner in a variety of veterinary species (see Doses) to treat infections that likely to be susceptible to a 3rd generation cephalosporin.

Ceftiofur sodiumSupplier

Anqing Hua Qi Chemical Technology Co., Ltd. Gold
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13721102221
Kunming AMK animal husbandry raw material operation department Gold
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347183002@qq.com
Hubei huizepu Pharmaceutical Technology Co., Ltd Gold
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1776-2444226-
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17762444226@163.com
Henan Huawen Chemical Co., Ltd Gold
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0370-2070108-
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2712427897@qq.com
Shanghai Boyle Chemical Co., Ltd.
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sales@boylechem.com