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CIVETONE

Basic information Safety Supplier Related

CIVETONE Basic information

Product Name:
CIVETONE
Synonyms:
  • (z)-9-cycloheptadecen-1-on
  • (Z)-9-Cycloheptadecen-1-one
  • 10-Ketocycloheptadecene
  • 10-Oxocycloheptadecene
  • 9-Cycloheptadecen-1-one,(Z)-
  • cis-9-cycloheptadecen-1-one
  • cis-Civetone
  • Zibeton
CAS:
542-46-1
MF:
C17H30O
MW:
250.42
EINECS:
208-813-4
Mol File:
542-46-1.mol
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CIVETONE Chemical Properties

Melting point:
31-32°
Boiling point:
bp742 342°; bp2 59°
Density 
d433 0.917
FEMA 
3425 | CYCLOHEPTADECA-9-EN-1-ONE
refractive index 
nD33.4 1.4830
Odor
at 1.00 % in dipropylene glycol. clean musk dry animal sweet
Odor Type
musk
JECFA Number
1401
LogP
6.31
EPA Substance Registry System
9-Cycloheptadecen-1-one, (9Z)- (542-46-1)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
38
Safety Statements 
36/37
Toxicity
The acute oral LD50 value in rats was reported as > 5 g/kg and the acute dermal LD50 value in rabbits exceeded 2 g/kg (Moreno. 1974).
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CIVETONE Usage And Synthesis

Chemical Properties

CIVETONE is a colorless liquid with warm, sensual, animalic musky odor and extreme tenacity. It is themain odoriferous constituent of civet.Civetonewas formerly prepared bymultistep syntheses, for example. Recently, newer processes using dimethyl (Z)-9-octadecendioate as starting material have been described. This is cyclized by a Dieckmann condensation either in liquid or in gaseous phase. (Z)-9-Octadecendioic acid is available by microbial oxidation of oleic acid with Candida tropicalis.
It is used in fine fragrance compositions for, for example, toiletries and body care products.

Chemical Properties

Cycloheptadeca-9-en-1-one has an obnoxious animal-gland odor. It can be pleasant at extreme dilutions.

Occurrence

In civet (cis-form).

Uses

In perfumery.

Preparation

From aleuritic acid, the trans- form only; the cis- and trans-forms from ethyl-9-keto heptadecanedioate.

Definition

ChEBI: A macrocycle that is cycloheptadecanone with an unsaturation at position 9 (the 9Z-stereoisomer). It has been found in African Civets.

Aroma threshold values

Detection: 3 ppb

Safety Profile

A skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.

CIVETONE Preparation Products And Raw materials

Raw materials

CIVETONESupplier

Hangzhou J&H Chemical Co., Ltd.
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0571-+86-571-87396432
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Alfa Chemistry
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1-516-6625404
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support@alfa-chemistry.com
Shenzhen Simeiquan Biotechnology Co. Ltd
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18126413629 0755-23311925 2355327053
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abel@ycgmp.com
Shenzhen Sendi Biological Technology Co., Ltd.
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18124570582 TEL:0755-23574479 2355327139
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siliao02@yccreate.com
Guangzhou Kafen Biotech Co.,Ltd
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18029243487 2355327168
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gy@yccreate.com