2-(2-BOC-AMINOETHOXY)ETHANOL Chemical Properties

Boiling point:

332.9±22.0 °C(Predicted)

Density 

1.061 g/mL at 25 °C

refractive index 

n20/D1.454

Flash point:

>110℃

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)

form 

clear liquid

pka

12.20±0.46(Predicted)

color 

Colorless to Light orange to Yellow

Safety Information

Hazard Codes 

T

Risk Statements 

25-36-37-38

Safety Statements 

36/39-45

RIDADR 

2810

WGK Germany 

3

HS Code 

2924.19.8000

HazardClass 

6.1

PackingGroup 

Ⅲ

2-(2-BOC-AMINOETHOXY)ETHANOL Usage And Synthesis

Description

N-Boc-PEG2-alcohol is a PEG linker containing a hydroxyl group and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Uses

2-[2-(Boc-amino)ethoxy]ethanol is N-terminal protected 2-(2-aminoethoxy)ethanol. It is generally used as a molecular spacer/linker. Some of such applications are:

• Synthesis of biotinylated HaloLigands to prepare quantum dot adducts for HaloTag protein-mediated specific labeling of live cells.
• It is one of the key precursors for the total synthesis of tyroscherin and photo-activatable tyroscherin-based affinity reagent used for identification of tyroscherin binding proteins.
• It can be used to link HaloTag enzyme with fluorescent zinc indicator, ZIMIR to monitor the dynamics of regulated secretion of zinc in real time.
• It can also be used to synthesize amphiphiles for DNA and siRNA delivery.

2-(2-BOC-AMINOETHOXY)ETHANOL(139115-91-6)Related Product Information

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