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DIHYDROERGOCRISTINE MESYLATE

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DIHYDROERGOCRISTINE MESYLATE Basic information

Product Name:
DIHYDROERGOCRISTINE MESYLATE
Synonyms:
  • (5’-alpha,10-alpha)-nylmethyl)monomethanesulfonate(salt)
  • (5'alpha, 10alpha)-9,10-Dihydro-12'-hydroxy-2'-(1-methylethyl)-5'-(phenylmethyl)-ergotaman-3',6',18-trione mesylate
  • C13168
  • (5'α,10α)-9,10-Dihydro-12'-hydroxy-2'-(1-methylethyl)-5'-(phenylmethyl)-ergotaman-3',6',18-trionemesylate
  • 9,10-dihydro-ergocristinmonomethanesulfonate(salt)
  • dihydroergocristinmesilat
  • ergotamane-3’,6’,18-trione,9,10-dihydro-12’-hydroxy-2’-(1-methylethyl)-5’-(phe
  • 5'alpha-benzyl-9,10alpha-dihydro-12'-hydroxy-2'-isopropylergotaman-3',6',18-trione monomethanesulphonate
CAS:
24730-10-7
MF:
C36H45N5O8S
MW:
707.84
EINECS:
246-434-6
Product Categories:
  • Organics
  • DID - DINDrugs of Abuse
  • ErgotamineForensic and Veterinary Standards
  • AlkaloidsAlphabetic
  • Chemical Structure
  • D
  • Drugs of Abuse
  • Drugs&Metabolites
  • Neat Compounds
  • Serotonin receptor
Mol File:
24730-10-7.mol
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DIHYDROERGOCRISTINE MESYLATE Chemical Properties

Melting point:
210 °C
storage temp. 
Store at RT
solubility 
H2O: 10 mg/mL
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Safety Information

RIDADR 
UN 1544 6.1/PG 2
WGK Germany 
2
RTECS 
KE7600000
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29396900

MSDS

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DIHYDROERGOCRISTINE MESYLATE Usage And Synthesis

Chemical Properties

White or almost white, fine crystalline powder.

Uses

5-HT receptor antagonist; partial agonist at adrenergic and dopaminergic receptors

Uses

Alpha receptor blocking

Uses

4,10-Dihydroergocristine Methanesulfonate is an nontoxic and well tolerated drug that exerts agonistic and antagonistic activity on dopaminergic and adrenergic receptors. 4,10-Dihydroergocristine Meth anesulfonate is known to exhibit protective properties to the brain against metabolic effects of ischemia by acting at a cellular level.

Definition

ChEBI: The methanesulfonic acid salt of dihydroergocristine. It has been used as the for the symptomatic treatment of mental deterioration associated with cerebrovascular insufficiency and in peripheral vascular disease. It is also a component of ergoloid mesylat (codergocrine mesilate), a mixture of ergot alkaloid derivatives that is used as a vasodilator and has shown mild benefits in the treatment of vascular dementia.

Biological Activity

5-HT receptor antagonist; partial agonist at adrenergic and dopaminergic receptors.

storage

Room temperature

DIHYDROERGOCRISTINE MESYLATESupplier

J & K SCIENTIFIC LTD.
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