ALPHA-ERGOCRYPTINE Chemical Properties

Melting point:

152-154°C

alpha 

D20 -120° (pyridine); -198° (chloroform)

Boiling point:

636.59°C (rough estimate)

Density 

1.1762 (rough estimate)

refractive index 

1.7500 (estimate)

storage temp. 

−20°C

solubility 

45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.3 mg/mL

form 

Solid

pka

9.61±0.60(Predicted)

color 

Pale Yellow to Pale Beige

Stability:

Hygroscopic

Safety Information

Hazard Codes 

Xn

Risk Statements 

62

Safety Statements 

36/37

RIDADR 

UN 1544 6.1/PG 3

WGK Germany 

3

RTECS 

KE1400000

HazardClass 

6.1(b)

PackingGroup 

III

ALPHA-ERGOCRYPTINE Usage And Synthesis

Chemical Properties

Pale Yellow Solid

Uses

α-Ergocryptine is an ergopeptine and one of the ergot alkaloids. An impurity of 2-Bromo α-Ergocryptine Mesylate (B682600).

Uses

An impurity of 2-Bromo α-Ergocriptine Mesylate (B682600).

Definition

ChEBI: Ergotaman bearing hydroxy, isopropyl, and 2-methylpropyl groups at the 12', 2' and 5' positions, respectively, and oxo groups at positions 3', 6', and 18. It is a natural ergot alkaloid. Ergocryptine discussed in the literature prior to 1967, when b ta-ergocryptine was separated from alpha-ergocryptine, is now referred to as alpha-ergocryptine.

Purification Methods

It crystallises with solvent of crystallisation, from acetone, *benzene or methanol. [Stadler et al. Helv Chim Acta 52 1549 1969, Beilstein 25 III/IV 964, 27 II 860.]

ALPHA-ERGOCRYPTINE(511-09-1)Related Product Information

• Ergotaman-3',6',18-trione, 2-bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-, (2'β,5'α,8α)- (9CI)
• BroMocriptine IMpurity G
• BroMocriptine-13C-d3
• BroMocriptine IMpurity F
• Ergoline-8-carboxylic acid, 2-bromo-9,10-didehydro-6-methyl-, (8β)-
• Ergocryptine, 2-bromo- (8CI),2-bromo-alpha-ergocryptin
• (8S)-2-BroMo α-Ergocryptine
• Bromocriptine mesylate
• BroMocriptine IMpurity E
• beta-ergocryptine
• Bromocriptine Impurity 2
• Bromocriptine Impurity A (Mixture of Diastereomers)
• DIHYDROERGOCRISTINE MESYLATE
• ERGTOXIN
• ALPHA-ERGOCRYPTINE
• Mergocriptine
• 1-Bromo-α-ergocryptine methane Sulfonate
• ergocryptine methanesulfonate