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(R)-Zanubrutinib

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(R)-Zanubrutinib Basic information

Product Name:
(R)-Zanubrutinib
Synonyms:
  • (R)-Zanubrutinib
  • (R)-BGB-3111
  • Pyrazolo[1,5-a]pyrimidine-3-carboxamide, 4,5,6,7-tetrahydro-7-[1-(1-oxo-2-propen-1-yl)-4-piperidinyl]-2-(4-phenoxyphenyl)-, (7R)-
  • Zanubrutinib Impurity 1 ((R)-Zanubrutinib)
  • (R) Zanubrutinib,(R)Zanubrutinib
  • Zanubrutinib impurity-12
  • (R)-7-(1-Acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5, 6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide
  • (R)-2-(4-phenoxyphenyl)-7-(piperidin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carbonitrile
CAS:
1691249-44-1
MF:
C27H29N5O3
MW:
471.55
Mol File:
1691249-44-1.mol
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(R)-Zanubrutinib Chemical Properties

Boiling point:
713.4±60.0 °C(Predicted)
Density 
1.33±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : ≥ 64.25 mg/mL (136.25 mM);Ethanol : < 1 mg/mL (insoluble)
form 
Solid
pka
15.35±0.40(Predicted)
color 
White to off-white
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(R)-Zanubrutinib Usage And Synthesis

Uses

(R)-Zanubrutinib, is the R enantiomer of Zanubrutinib, which is a selective Bruton tyrosine kinase (BTK) inhibitor.

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