Basic information Safety Supplier Related

(+)-(S,R)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran

Basic information Safety Supplier Related

(+)-(S,R)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran Basic information

Product Name:
(+)-(S,R)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran
Synonyms:
  • (S)-6-fluoro-2-((R)-oxiran-2-yl)chroman
  • (2S, 2’R)-6-Fluoro-2-(2’-oxiranyl)chromane
  • 2H-1-Benzopyran, 6-fluoro-3,4-dihydro-2-[(2R)-2-oxiranyl]-, (2S)-
  • Nebivolol Impurity 10
  • A-Isomer Nebivolol
  • Nebivolol Isomer-A
  • Nebivolol A Isomer (Nebivolol Imp-28)
  • (+)-(S,R)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran
CAS:
197706-51-7
MF:
C11H11FO2
MW:
194.2
EINECS:
606-374-7
Mol File:
197706-51-7.mol
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(+)-(S,R)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran Chemical Properties

Boiling point:
285.4℃ at 102kPa
Density 
1.38g/cm3 at 20℃
vapor pressure 
0.21-0.4Pa at 20-25℃
form 
Solid
LogP
2.5-3.2 at pH7
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(+)-(S,R)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran Usage And Synthesis

Uses

(2S,2’R)-6-Fluoro-2-(2’-oxiranyl)chromane is an intermediate to synthesize Nebivolol (rac, HCl salt, N387900) which is a β1-Adrenergic blocker.

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(+)-(S,R)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran(197706-51-7)Related Product Information