Basic information Safety Supplier Related

Nifedipine Pyrimidine Impurity

Basic information Safety Supplier Related

Nifedipine Pyrimidine Impurity Basic information

Product Name:
Nifedipine Pyrimidine Impurity
Synonyms:
  • Pyrimidine impurity
  • Nifedipine Pyrimidine Impurity
  • 5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-6-methyl-2,4-bis(2-nitrophenyl)-, methyl ester, (2R,4R)-rel-
  • Methyl cis-1,2,3,4-tetrahydro-6-methyl-2,4-bis(2-nitrophenyl)-5-pyrimidinecarboxylate
  • rel-Methyl(2R,4R)-1,2,3,4-tetrahydro-6-methyl-2,4-bis(2-nitrophenyl)-5-pyrimidinecarboxylate
  • Nifedipine EP Impurity 7
CAS:
80742-11-6
MF:
C19H18N4O6
MW:
398.37
Mol File:
80742-11-6.mol
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Nifedipine Pyrimidine Impurity Chemical Properties

Boiling point:
572.8±50.0 °C(Predicted)
Density 
1.339±0.06 g/cm3(Predicted)
solubility 
DMSO (Slightly), Ethyl Acetate (Very Slightly, Heated), Methanol (Slightly)
form 
Solid
pka
4.14±0.70(Predicted)
color 
Pale Yellow to Light Yellow
Stability:
Light Sensitive
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Nifedipine Pyrimidine Impurity Usage And Synthesis

Uses

(2R,4R)-rel-1,2,3,4-Tetrahydro-6-methyl-2,4-bis(2-nitrophenyl)-5-pyrimidinecarboxylic Acid Methyl Ester is an impurity of Nifedipine (N457000); a dihydropyridine calcium channel blocker. Also used as an antihypertensive and antianginal.

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