3-BENZYL-5-(2-HYDROXYETHYL)-4-METHYLTHIAZOLIUM CHLORIDE Chemical Properties

Melting point:

142-144 °C(lit.)

storage temp. 

Inert atmosphere,Room Temperature

solubility 

sol H2O, MeOH, EtOH; slightly sol cold MeCN; insol ether, pentane

form 

Crystalline Powder

color 

White

Water Solubility 

Soluble in water.

Sensitive 

Hygroscopic

BRN 

3788921

InChI

InChI=1S/C13H16NOS.ClH/c1-11-13(7-8-15)16-10-14(11)9-12-5-3-2-4-6-12;/h2-6,10,15H,7-9H2,1H3;1H/q+1;/p-1

InChIKey

IWSVLBKHBJGMAA-UHFFFAOYSA-M

SMILES

[N+]1(=CSC(CCO)=C1C)CC1=CC=CC=C1.[Cl-]

CAS DataBase Reference

4568-71-2(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HS Code 

29341000

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

3-BENZYL-5-(2-HYDROXYETHYL)-4-METHYLTHIAZOLIUM CHLORIDE Usage And Synthesis

Uses

3-Benzyl-5-(2-hydroxyethyl)-4-methylthiazolium chloride, aliphatic aldehydes undergo the acyloin condensation in the presence of this catalyst and mild base. It acts as a catalyst for the addition of aliphatic and heterocyclic aldehydes to α,β-unsaturated ketones, nitriles and esters.

Purification Methods

Purify the chloride by recrystallisation from EtOH or H2O. If placed in a bath at 125o and heated at 2o/minute, the melting point is 140.5-141.4o. [Livermore & Sealock J Biol Chem 167 699 1947, Maier & Metzler J Am Chem Soc 79 4386 1957, Beilstein 27 III/IV 1758.]

3-BENZYL-5-(2-HYDROXYETHYL)-4-METHYLTHIAZOLIUM CHLORIDE(4568-71-2)Related Product Information

• 2,2'-Dithiobis(benzothiazole)
• Lithium chloride
• Lithium
• 4,5-Dimethylthiazole
• 3-BENZYL-4-METHYLTHIAZOLIUM CHLORIDE
• 5-Methylthiazole
• 5-(2-Hydroxyethyl)-4-methylthiazole
• 5-ethyl-4-methylthiazole
• 3-BENZYL-5-(2-HYDROXYETHYL)-4-METHYLTHIAZOLIUM CHLORIDE