Basic information Safety Supplier Related

(+/-)AMETHOPTERIN

Basic information Safety Supplier Related

(+/-)AMETHOPTERIN Basic information

Product Name:
(+/-)AMETHOPTERIN
Synonyms:
  • 6-mtx(dl)
  • dl-amethopterin
  • dl-methotrexate
  • n-(p-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-dl-glutamicacid
  • AKOS 93273
  • (+/-)AMETHOPTERIN
  • DL-4-Amino-N10-methylpteroylglutamic acid
  • (plus-minus)-amethopterin
CAS:
60388-53-6
MF:
C20H22N8O5
MW:
454.44
EINECS:
262-213-7
Product Categories:
  • RHEUMATREX
Mol File:
60388-53-6.mol
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(+/-)AMETHOPTERIN Chemical Properties

Melting point:
195 °C (dec.)(lit.)
Density 
1.536±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
H2O: Add a minimal amount of 0.1 L NaOH to solubilize, then dilute in neutral buffer or saline. Diluted stock is stable for 1week refrigerated and for 1month frozen at?20°C.
form 
powder
pka
3.47±0.10(Predicted)
color 
yellow
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Safety Information

Hazard Codes 
T
Risk Statements 
61-25-36/38-23/24/25
Safety Statements 
53-26-36/37-45-36/37/39
RIDADR 
UN 1544 6.1/PG 2
WGK Germany 
3
RTECS 
MA1224100

MSDS

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(+/-)AMETHOPTERIN Usage And Synthesis

Chemical Properties

yellow to orange crystalline powder

Uses

Racemic Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic.

Uses

(+/-)Amethopterin is a folic acid antagonist and anticancer agent.

Uses

Amethopterin is an antineoplastic, antirheumatic, folic acid antagonist

Definition

ChEBI: 2-[[[4-[(2,4-diamino-6-pteridinyl)methyl-methylamino]phenyl]-oxomethyl]amino]pentanedioic acid is a member of folic acids.

(+/-)AMETHOPTERINSupplier

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