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D(-)-AMETHOPTERIN

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D(-)-AMETHOPTERIN Basic information

Product Name:
D(-)-AMETHOPTERIN
Synonyms:
  • d-methotrexate
  • n-(4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-d-glutamicacid
  • D(-)-AMETHOPTERIN
  • D-(-)-AMETHOPTERIN HYDRATE
  • D(-)-4-AMINO-N10-METHYLPTEROYLGLUTAMIC ACID
  • D-(-)-N-(2,4-diamino-6-pteridinyl(dimethylamino)benzoyl)glutamic acid
  • R-Methotrexate (5 mg) ((R)-2-(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzamido)pentanedioic acid)
  • R-Methotrexate
CAS:
51865-79-3
MF:
C20H22N8O5
MW:
454.44
EINECS:
257-482-2
Mol File:
51865-79-3.mol
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D(-)-AMETHOPTERIN Chemical Properties

Melting point:
195 °C
Boiling point:
561.26°C (rough estimate)
Density 
1.4080 (rough estimate)
refractive index 
1.6910 (estimate)
storage temp. 
-20°C
solubility 
Aqueous Base (Slightly, Heated, Sonicated), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
3.47±0.10(Predicted)
color 
Dark Yellow to Very Dark Yellow
Stability:
Hygroscopic
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Safety Information

Hazard Codes 
T
Risk Statements 
61-46-25-36/37/38-60-23/24/25
Safety Statements 
53-45-28A-36/37/39-26-22
RIDADR 
UN 1544 6.1/PG 3
RTECS 
MA1224000
HS Code 
29335995

MSDS

  • Language:English Provider:ACROS
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D(-)-AMETHOPTERIN Usage And Synthesis

Chemical Properties

Solid

Uses

R-Methotrexate is an enantiomer of Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic.

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