(+/-)AMETHOPTERIN

Product Name: (+/-)AMETHOPTERIN
CAS No.: 60388-53-6
Chemical Name: (+/-)AMETHOPTERIN
Synonyms: dl-MTX;6-mtx(dl);AKOS 93273;NSC 117356;-)AMETHOPTERIN;dl-methotrexate;dl-amethopterin;(+/-)AMETHOPTERIN;dl-Methylaminopterin;Methotrexate Impurity 3
CBNumber: CB7749012
Molecular Formula: C20H22N8O5
Formula Weight: 454.44
MOL File: 60388-53-6.mol

More

Less

(+/-)AMETHOPTERIN Property

Melting point:: 195 °C (dec.)(lit.)
Density: 1.536±0.06 g/cm3(Predicted)
storage temp.: −20°C
solubility: H2O: Add a minimal amount of 0.1 L NaOH to solubilize, then dilute in neutral buffer or saline. Diluted stock is stable for 1week refrigerated and for 1month frozen at?20°C.
form: powder
pka: 3.47±0.10(Predicted)
color: yellow

More

Less

Safety

Hazard Codes: T
Risk Statements: 61-25-36/38-23/24/25
Safety Statements: 53-26-36/37-45-36/37/39
RIDADR: UN 1544 6.1/PG 2
WGK Germany: 3
RTECS: MA1224100

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: M260680
Product name: DL-MethotrexateDipotassiumSaltDihydrate
Packaging: 250mg
Price: $1190
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0002442
Product name: DL-AMETHOPTERIN
Purity: 95.00%
Packaging: 100MG
Price: $636.16
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 52125
Product name: DL-MethotrexateDipotassiumSaltDihydrate
Packaging: 25mg
Price: $650
Updated: 2021/12/16

AvaChem

Product number: 3936
Product name: Racemethotrexate
Packaging: 10mg
Price: $39
Updated: 2021/12/16

AvaChem

Product number: 3936
Product name: Racemethotrexate
Packaging: 25mg
Price: $59
Updated: 2021/12/16

More

Less

(+/-)AMETHOPTERIN Chemical Properties,Usage,Production

Chemical Properties

yellow to orange crystalline powder

Uses

Racemic Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic.

Uses

(+/-)Amethopterin is a folic acid antagonist and anticancer agent.

Uses

Amethopterin is an antineoplastic, antirheumatic, folic acid antagonist

Definition

ChEBI: 2-[[[4-[(2,4-diamino-6-pteridinyl)methyl-methylamino]phenyl]-oxomethyl]amino]pentanedioic acid is a member of folic acids.

(+/-)AMETHOPTERIN Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

(+/-)AMETHOPTERIN Suppliers

Belgium 1 Canada 1 China 51 France 1 Germany 3 India 3 Japan 1 Switzerland 1 Ukraine 1 United Kingdom 2 United States 14 Global 79

Tianjin Baima Technology Co., LTD

Tel: 022-88195255 15620955089
Email: 362698781@qq.com
Country: China
ProdList: 785
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94838
Advantage: 76

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32344
Advantage: 50

BEST-REAGENT

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11726
Advantage: 57

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9823
Advantage: 79

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22519
Advantage: 55

Shanghai TaoSu Biochemical Technology Co., Ltd.

Tel: 021-33632979
Fax: 021-34692979
Email: info@tsbiochem.com
Country: China
ProdList: 8073
Advantage: 58

Shanghai JONLN Reagent Co., Ltd.

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: 422131432@qq.com
Country: China
ProdList: 9986
Advantage: 55

Shanghai Kewel Chemical Co., Ltd.

Tel: 021-64609169 18901607656
Fax: 021-64609160
Email: greensnown@163.com
Country: China
ProdList: 9911
Advantage: 50

klamar reagent

Tel: 4001650900
Fax: 021-64897811
Email: sales-wang@klamar-reagent.com
Country: China
ProdList: 1986
Advantage: 55

60388-53-6, (+/-)AMETHOPTERINRelated Search:

(+/-)AMETHOPTERIN Methotrexate sodium Methotrexate L-AMETHOPTERIN HYDRATE,L-(+)-AMETHOPTERIN HYDRATE,(+)-AMETHOPTERIN HYDRATE DL-Glutamic acid Folic acid Dichloromethotrexate METHOTREXATE DIMETHYL ESTER 7-CYANOMETHOTREXATE DIMETHYL ESTER 7-Hydroxy Amethopterin-d3 4-Amino-7-hydroxy-10-methylpteroylglutamic Acid-d3 METHOTREXATE-D3 METHOTREXATE SODIUM SALT, [3',5',7'-3H] 7-Hydroxy Amethopterin, 4-Amino-7-hydroxy-10-methylpteroylglutamic Acid D-AMETHOPTERIN HYDRATE, 95 (-) - AMETHOPTERIN - D - METHOTREXATE,D(-)-AMETHOPTERIN,D-(-)-AMETHOPTERIN HYDRATE D(-)-AMETHOPTERIN HYDRATE, 98 DL-AMETHOPTERIN HYDRATE Fluoromethotrexate

6-mtx(dl)

dl-amethopterin

dl-methotrexate

n-(p-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-dl-glutamicacid

AKOS 93273

(+/-)AMETHOPTERIN

DL-4-Amino-N10-methylpteroylglutamic acid

(plus-minus)-amethopterin

N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-DL-glutamic acid

DL-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-

Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]- (9CI)

NSC 117356

dl-Methylaminopterin

dl-MTX

DL-Amethopterin hydrate,95%

(±)Amethopterin hydrate,4-Amino-10-methylfolic acid, DL-4-Amino-N10-methylpteroylglutamic acid, MTX, Methylaminopterin

(plus-Minus)-aMethopterin(-20`C)

DL-Methotrexate DipotassiuM Salt Dihydrate

Methotrexate Impurity 3

Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-

-)AMETHOPTERIN

2-(4-(((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)pentanedioic acid

MethotrexateImpurity3-d3

60388-53-6

C20H22N8O5xxH2O

DNA Synthesis Inhibitors

DNA metabolism

Apoptosis and Cell Cycle

Cell Signaling and Neuroscience

Cell Biology

BioChemical

RHEUMATREX