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(+/-)AMETHOPTERIN

Product Name
(+/-)AMETHOPTERIN
CAS No.
60388-53-6
Chemical Name
(+/-)AMETHOPTERIN
Synonyms
dl-MTX;6-mtx(dl);AKOS 93273;NSC 117356;-)AMETHOPTERIN;dl-methotrexate;dl-amethopterin;(+/-)AMETHOPTERIN;dl-Methylaminopterin;Methotrexate Impurity 3
CBNumber
CB7749012
Molecular Formula
C20H22N8O5
Formula Weight
454.44
MOL File
60388-53-6.mol
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(+/-)AMETHOPTERIN Property

Melting point:
195 °C (dec.)(lit.)
Density 
1.536±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
H2O: Add a minimal amount of 0.1 L NaOH to solubilize, then dilute in neutral buffer or saline. Diluted stock is stable for 1week refrigerated and for 1month frozen at?20°C.
form 
powder
pka
3.47±0.10(Predicted)
color 
yellow
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Safety

Hazard Codes 
T
Risk Statements 
61-25-36/38-23/24/25
Safety Statements 
53-26-36/37-45-36/37/39
RIDADR 
UN 1544 6.1/PG 2
WGK Germany 
3
RTECS 
MA1224100
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
M260680
Product name
DL-MethotrexateDipotassiumSaltDihydrate
Packaging
250mg
Price
$1190
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0002442
Product name
DL-AMETHOPTERIN
Purity
95.00%
Packaging
100MG
Price
$636.16
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
52125
Product name
DL-MethotrexateDipotassiumSaltDihydrate
Packaging
25mg
Price
$650
Updated
2021/12/16
AvaChem
Product number
3936
Product name
Racemethotrexate
Packaging
10mg
Price
$39
Updated
2021/12/16
AvaChem
Product number
3936
Product name
Racemethotrexate
Packaging
25mg
Price
$59
Updated
2021/12/16
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(+/-)AMETHOPTERIN Chemical Properties,Usage,Production

Chemical Properties

yellow to orange crystalline powder

Uses

Racemic Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic.

Uses

(+/-)Amethopterin is a folic acid antagonist and anticancer agent.

Uses

Amethopterin is an antineoplastic, antirheumatic, folic acid antagonist

Definition

ChEBI: 2-[[[4-[(2,4-diamino-6-pteridinyl)methyl-methylamino]phenyl]-oxomethyl]amino]pentanedioic acid is a member of folic acids.

(+/-)AMETHOPTERIN Preparation Products And Raw materials

Raw materials

Preparation Products

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60388-53-6, (+/-)AMETHOPTERINRelated Search:

(+/-)AMETHOPTERIN Methotrexate sodium Methotrexate L-AMETHOPTERIN HYDRATE,L-(+)-AMETHOPTERIN HYDRATE,(+)-AMETHOPTERIN HYDRATE DL-Glutamic acid Folic acid Dichloromethotrexate METHOTREXATE DIMETHYL ESTER 7-CYANOMETHOTREXATE DIMETHYL ESTER 7-Hydroxy Amethopterin-d3 4-Amino-7-hydroxy-10-methylpteroylglutamic Acid-d3 METHOTREXATE-D3 METHOTREXATE SODIUM SALT, [3',5',7'-3H] 7-Hydroxy Amethopterin, 4-Amino-7-hydroxy-10-methylpteroylglutamic Acid D-AMETHOPTERIN HYDRATE, 95 (-) - AMETHOPTERIN - D - METHOTREXATE,D(-)-AMETHOPTERIN,D-(-)-AMETHOPTERIN HYDRATE D(-)-AMETHOPTERIN HYDRATE, 98 DL-AMETHOPTERIN HYDRATE Fluoromethotrexate

  • 6-mtx(dl)
  • dl-amethopterin
  • dl-methotrexate
  • n-(p-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-dl-glutamicacid
  • AKOS 93273
  • (+/-)AMETHOPTERIN
  • DL-4-Amino-N10-methylpteroylglutamic acid
  • (plus-minus)-amethopterin
  • N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-DL-glutamic acid
  • DL-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-
  • Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]- (9CI)
  • NSC 117356
  • dl-Methylaminopterin
  • dl-MTX
  • DL-Amethopterin hydrate,95%
  • (±)Amethopterin hydrate,4-Amino-10-methylfolic acid, DL-4-Amino-N10-methylpteroylglutamic acid, MTX, Methylaminopterin
  • (plus-Minus)-aMethopterin(-20`C)
  • DL-Methotrexate DipotassiuM Salt Dihydrate
  • Methotrexate Impurity 3
  • Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-
  • -)AMETHOPTERIN
  • 2-(4-(((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)pentanedioic acid
  • MethotrexateImpurity3-d3
  • 60388-53-6
  • C20H22N8O5xxH2O
  • DNA Synthesis Inhibitors
  • DNA metabolism
  • Apoptosis and Cell Cycle
  • Cell Signaling and Neuroscience
  • Cell Biology
  • BioChemical
  • RHEUMATREX