OZAGREL HYDROCHLORIDE
OZAGREL HYDROCHLORIDE Basic information
- Product Name:
- OZAGREL HYDROCHLORIDE
- Synonyms:
-
- (2E)-3-[4-(1H-IMIDAZOL-1-YLMETHYL)PHENYL]-2-PROPENOIC ACID HYDROCHLORIDE
- OZAGREL HCL
- Zinc00005389
- Ozagrel Impurity 46
- Ozagrel HydrochlorideQ: What is Ozagrel Hydrochloride Q: What is the CAS Number of Ozagrel Hydrochloride Q: What is the storage condition of Ozagrel Hydrochloride Q: What are the applications of Ozagrel Hydrochloride
- CAS:
- 74003-18-2
- MF:
- C13H13ClN2O2
- MW:
- 264.71
- Product Categories:
-
- Prostanoid receptor and related
- Mol File:
- 74003-18-2.mol
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OZAGREL HYDROCHLORIDE Chemical Properties
- storage temp.
- Store at RT
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OZAGREL HYDROCHLORIDE Usage And Synthesis
Uses
Ozagrel Hydrochloride is a selective thromboxane A2 synthase inhibitor, which alleviates liver injury induced by acetaminophen overdose in mice.
Definition
ChEBI: Ozagrel hydrochloride is an organic molecular entity.
Biological Activity
Potent and selective inhibitor of thromboxane (TXA 2 ) synthetase (IC 50 = 4 nM). Does not inhibit prostacyclin (PGI 2 ) synthetase, cyclooxygenase or PGE 2 isomerase (IC 50 > 1 mM). Inhibits platelet aggregation in vitro and arachidonate-induced arterial contraction in vivo .
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