Cergutuzumab Amunaleukin
Cergutuzumab Amunaleukin Basic information
- Product Name:
- Cergutuzumab Amunaleukin
- Synonyms:
-
- Cergutuzumab Amunaleukin
- Research Grade Cergutuzumab (DHC21002)
- Research Grade Cergutuzumab
- Cergutuzumab
- Cergutuzumab (anti-CEACAM5)
- CAS:
- 1509916-03-3
- MW:
- 0
- Mol File:
- Mol File
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Cergutuzumab Amunaleukin Chemical Properties
- form
- Liquid
- color
- Colorless to off-white
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Cergutuzumab Amunaleukin Usage And Synthesis
Uses
Cergutuzumab amunaleukin (CEA-IL2v) is a monomeric carcinoembryonic antigen (CEA)-targeted IL-2 variant-based immunocytokine. Cergutuzumab amunaleukin has immunostimulating and antineoplastic activities[1].
in vivo
In tumor-free mice, a strong expansion of peripheral CD8+ T and NK cells after treatment with 0.5 and 2 mg/kg Cergutuzumab amunaleukin (CEA-IL2v; i.v.; once) is observed[1].
References
[1] Christian Klein, et al. Cergutuzumab amunaleukin (CEA-IL2v), a CEA-targeted IL-2 variant-based immunocytokine for combination cancer immunotherapy: Overcoming limitations of aldesleukin and conventional IL-2-based immunocytokines. Oncoimmunology. 2017 Jan 11;6(3):e1277306. DOI:10.1080/2162402X.2016.1277306
Cergutuzumab AmunaleukinSupplier
Shanghai YuanYe Biotechnology Co., Ltd.
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Shanghai Han-Xiang Chemical Co., Ltd.
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- 15971444841
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TargetMol Chemicals Inc.
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Guangzhou Hongyuan Chemical Co.,Ltd
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Wuhan Chemstan Biotechnology Co., Ltd.
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