Immunoglobulin G2/G4, anti-(human complement C5) (human-Mus musculus ALXN1210 heavy chain), disulfide with human-Mus musculus ALXN1210 κ-chain, dimer Chemical Properties

form 

Liquid

color 

Colorless to light yellow

Immunoglobulin G2/G4, anti-(human complement C5) (human-Mus musculus ALXN1210 heavy chain), disulfide with human-Mus musculus ALXN1210 κ-chain, dimer Usage And Synthesis

Uses

Ravulizumab (ALXN1210) is a humanized monoclonal antibody that specifically binds with high affinity to the human complement protein C5. Ravulizumab can be used for the research of paroxysmal nocturnal hemoglobinuria, atypical hemolytic uremic syndrome, and myasthenia gravis[1].

References

[1] Lee JW, et, al. Ravulizumab (ALXN1210) vs eculizumab in adult patients with PNH naive to complement inhibitors: the 301 study. Blood. 2019 Feb 7;133(6):530-539. DOI:10.1182/blood-2018-09-876136

Immunoglobulin G2/G4, anti-(human complement C5) (human-Mus musculus ALXN1210 heavy chain), disulfide with human-Mus musculus ALXN1210 κ-chain, dimer(1803171-55-2)Related Product Information

• Larcaviximab
• Laprituximab
• Fidasimtamab
• Research Grade Acazicolcept (DHC83404)
• Iscalimab
• Rosmantuzumab
• Anrukinzumab
• Nirsevimab
• Trinbelimab
• Lupartumab