2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one
2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one Basic information
- Product Name:
- 2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one
- Synonyms:
-
- 2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one
- 4-[4-[4-(4-Methoxyphenyl)piperazino]phenyl]-3,4-dihydro-2H-1,2,4-triazole-3-one
- Posaconazole inter-5
- 4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-1H-1,2,4-triazol-5-one
- 2,4-DIHYDRO-4-[4-[4-(4-METHOXYPHENYL)PIPERAZIN-1-YL]PHENYL]-3H-1,2,4-TRIAZOL-3-ONE(WXC08779)
- 4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-1H-1,2,4-triazol-5-one
- 3H-1,2,4-Triazol-3-one,2,4-dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-
- 4-(4-(4-(4-methoxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one
- CAS:
- 74853-07-9
- MF:
- C19H21N5O2
- MW:
- 351.4
- EINECS:
- 278-009-6
- Product Categories:
-
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Mol File:
- 74853-07-9.mol
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2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one Chemical Properties
- Melting point:
- 270-277°C (dec.)
- Density
- 1.30±0.1 g/cm3(Predicted)
- vapor pressure
- 0-0Pa at 20-25℃
- storage temp.
- Sealed in dry,2-8°C
- solubility
- DMSO (Slightly, Heated)
- form
- Solid:particulate/powder
- pka
- 10.16±0.20(Predicted)
- LogP
- 2.3 at pH7
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2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one Usage And Synthesis
Chemical Properties
Off-White Solid
Uses
4-{[4-(4-Methyloxyphenyl)-piperazin-1-yl]-phenyl}-2,4-dihydro-[1,2,4]-triazol-3-one, is an intermediate for the synthesis of Itraconazole (I937500), an Antifungal.
2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-oneSupplier
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2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one(74853-07-9)Related Product Information
- Posaconazole
- Posaconazole Diastereoisomer 12
- Posaconazole-d4
- Posaconazole DiastereoisoMer interMediate 2
- 1H-1,2,4-TRIAZOLE, 1-[[(2S)-2-(2,4-DIFLUOROPHENYL)OXIRANYL]METHYL]-
- Posaconazole-d5
- 2,4-Dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one
- 2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one
- Itraconazole
- HYDROXY ITRACONAZOLE
- SAPERCONAZOLE
- KETO ITRACONAZOLE
- 3H-1,2,4-TRIAZOL-3-ONE, 2,4-DIHYDRO-4-[4-[4-(4-METHOXYPHENYL)-1-PIPERAZINYL]PHENYL]-2-(1-METHYLPROPYL)-, (S)-
- ITRACONAZOLE-5-METHYL-2-ISOPENTANE
- MITRATAPID
- BENZYL HYDROXY ITRACONAZOLE
- 3H-1,2,4-TRIAZOL-3-ONE, 2,4-DIHYDRO-4-[4-[4-(4-METHOXYPHENYL)-1-PIPERAZINYL]PHENYL]-2-(1-METHYLPROPYL)-, (R)-
- 2-SEC-BUTYL-D5-4-(4-[4-(4-METHYLOXY-PHENYL)-PIPERAZIN-1-YL]-PHENYL)-2,4-DIHYDRO-[1,2,4]-TRIAZOL-3-ONE