2H-1-Benzopyran-2-one, 3-[2-[(3-acetylphenyl)amino]-4-thiazolyl]- Chemical Properties

Boiling point:

605.2±65.0 °C(Predicted)

Density 

1.396±0.06 g/cm3(Predicted)

form 

Solid

pka

2.66±0.10(Predicted)

color 

Light yellow to yellow

2H-1-Benzopyran-2-one, 3-[2-[(3-acetylphenyl)amino]-4-thiazolyl]- Usage And Synthesis

Uses

ZINC00784494 is a specific Lipocalin-2 (LCN2) inhibitor. ZINC00784494 inhibits cell proliferation, cell viability and reduces AKT phosphorylation levels in SUM149 cells. ZINC00784494 has good potential for research in inflammatory breast cancer (IBC)[1].

References

[1] Santiago-Sánchez GS, et al. Targeting Lipocalin-2 in Inflammatory Breast Cancer Cells with Small Interference RNA and Small Molecule Inhibitors. Int J Mol Sci. 2021 Aug 10;22(16):8581. DOI:10.3390/ijms22168581

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