ChemicalBook > Product Catalog > Pharmaceutical intermediates > Heterocyclic compound > Pyrimidines > Fluoropyrimidine > Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate
Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate
Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate Basic information
- Product Name:
- Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate
- Synonyms:
-
- BUTTPARK 46\18-97
- METHYL 2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE
- Methyl2-chloro-4-(trifluoromethyl)pyrimidine-5-
- 4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]-2-methylbenzoate
- Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-
- Methyl 2-Chloro-4-(trif1uoromethyl) pyridine-5-carboxylate
- Methyl 2-chloro-4-(trifluoromethyl)-5-pyrimidinecarboxylate
- 2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic acid methyl ester
- CAS:
- 175137-27-6
- MF:
- C7H4ClF3N2O2
- MW:
- 240.57
- Product Categories:
-
- Esters
- Pyrazines, Pyrimidines & Pyridazines
- Heterocycle
- Mol File:
- 175137-27-6.mol
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Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate Chemical Properties
- Melting point:
- 253-254 °C
- Boiling point:
- 76-78°C 0,5mm
- Density
- 1.491
- refractive index
- n20/D1.468
- Flash point:
- >110℃
- storage temp.
- 2-8°C
- pka
- -5.70±0.29(Predicted)
- CAS DataBase Reference
- 175137-27-6(CAS DataBase Reference)
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Safety Information
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-20/21/22-22
- Safety Statements
- 26-36/37/39-23-51-24/25-22
- RIDADR
- UN 2810 6.1 / PGIII
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 2933599590
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Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate Usage And Synthesis
Uses
Methyl 2-Chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate is used in the synthetic preparation and discovery of 2-[(2,4-Dichlorophenyl)amino]-N-[(tetrahydro- 2H-pyran-4-yl)methyl]-4-(trifluoromethyl)- 5-pyrimidinecarboxamide (G931520) which is a highly selective CB2 receptor agonist for the treatment of inflammatory and neuropathic pain.
Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylateSupplier
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Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate(175137-27-6)Related Product Information
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- ETHYL 2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE
- METHYL PYRIMIDINE-5-CARBOXYLATE
- 2-Chloro-4-(trifluoromethyl)pyrimidine
- BENZYL 2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE