2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-[1-(phenylmethyl)-4-piperidinyl]-2H-isoindol-2-yl]-
2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-[1-(phenylmethyl)-4-piperidinyl]-2H-isoindol-2-yl]- Basic information
- Product Name:
- 2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-[1-(phenylmethyl)-4-piperidinyl]-2H-isoindol-2-yl]-
- Synonyms:
-
- 2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-[1-(phenylmethyl)-4-piperidinyl]-2H-isoindol-2-yl]-
- NVPDKY709,NVP-DKY-709,NVP DKY709
- DKY709
- 3-(5-(1-Benzylpiperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione , NVP-DKY709
- CAS:
- 2291360-73-9
- MF:
- C25H27N3O3
- MW:
- 417.5
- Mol File:
- 2291360-73-9.mol
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2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-[1-(phenylmethyl)-4-piperidinyl]-2H-isoindol-2-yl]- Chemical Properties
- Boiling point:
- 661.8±55.0 °C(Predicted)
- Density
- 1.281±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO : 62.5 mg/mL (149.70 mM; ultrasonic and warming and heat to 60°C)
- form
- Solid
- pka
- 10.73±0.40(Predicted)
- color
- White to off-white
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2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-[1-(phenylmethyl)-4-piperidinyl]-2H-isoindol-2-yl]- Usage And Synthesis
Biological Activity
NVP-DKY709 is a potent IKZF2 inhibitor for the treatment of cancers.
References
[1]. Simone BONAZZI, et al. Dosing regimen and pharmaceutical combination comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives. WO2020128972 A1.
2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-[1-(phenylmethyl)-4-piperidinyl]-2H-isoindol-2-yl]-Supplier
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