L-TETRANDRINE
L-TETRANDRINE Basic information
- Product Name:
- L-TETRANDRINE
- Synonyms:
-
- L-TETRANDRINE
- PHAENTHINE
- Pheanthine
- 16H-1,24:6,9-Dietheno-11,15-metheno-2H-pyrido[2',3':17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline, 3,4,4a,5,16a,17,18,19-octahydro-12,21,22,26-tetramethoxy-4,17-dimethyl-, (4aR,16aR)-
- (-)-Phaeanthine
- Pheanthine, 10 mM in DMSO
- CAS:
- 1263-79-2
- MF:
- C38H42N2O6
- MW:
- 622.75
- Mol File:
- 1263-79-2.mol
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L-TETRANDRINE Chemical Properties
- Melting point:
- 210°
- alpha
- D20 -278° (chloroform)
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L-TETRANDRINE Usage And Synthesis
Uses
Pheanthine (Compound 2) is an antiplasmodial agent, that inhibits chloroquine-resistant Plasmodium falciparum K-1 (IC50 is 0.8 μM) and chloroquine-sensitive P. falciparum strain NF54 A19A (IC50 of 0.03 μM). Pheanthine exhibits low cytotoxicity in human lung fibrosblast (MRC-5, IC50 is 11.2 μM) and macrophages (PMM, IC50 is 8 μM)[1].
References
[1] Cimanga Kanyanga R., et al.,Isolation and structure elucidation of two antiprotozoal bisbenzylisoquinoline alkaloids from Triclisia gilletii stem bark. Phytochemistry Letters. 2018.
L-TETRANDRINESupplier
TargetMol Chemicals Inc.
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
Shaanxi Dideu Medichem Co. Ltd
- Tel
- +86-29-81148696 +86-15536356810
- 1022@dideu.com
Shanghai Yifei Biotechnology Co. , Ltd.
- Tel
- 021-65675885 18964387627
- customer_service@efebio.com
TargetMol Chemicals Inc.
- Tel
- 15002134094
- marketing@targetmol.cn
Sangon Biotech (Shanghai) Co.,Ltd.
- Tel
- 400-821-026
- Sales@sangon.com
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L-TETRANDRINE(1263-79-2)Related Product Information
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- (S)-1-(3,4-Dimethoxyphenyl)ethylamine
- SALSOLIDINE
- TETRANDRINE, (S,S)-(+)-(RG),(S S)-(+)-TETRANDRINE 98%,d-tetrandrine,(S,S)-(+)-TETRANDRINE,TETRANDRINE, (S,S)-(+),(+)-TETRANDRINE,TETRANDRINE
- (S)-7-METHOXY-1-METHYL-1,2,3,4-TETRAHYDRO-ISOQUINOLIN-6-OL
- 3-PHENOXYPHENETHYLAMINE
- Cresol
- 2,4-Dimethoxybenzylamine
- 2,3,4-Trimethoxybenzylamine
- N-Methyl-3-phenoxybenzylamine
- 3,4'-DIMETHYLDIPHENYL ETHER
- (S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol
- Demethyl tetrandrine
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- L-TETRANDRINE
- 8-methoxy-1,2,3,4-tetrahydroisoquinoline
- Benzenemethanamine, 2,3,4-trimethoxy-a-methyl-,(S)-