Basic information Safety Supplier Related

2,4-Dimethoxybenzylamine

Basic information Safety Supplier Related

2,4-Dimethoxybenzylamine Basic information

Product Name:
2,4-Dimethoxybenzylamine
Synonyms:
  • RARECHEM AL BW 0348
  • RARECHEM AL BW 0153
  • AURORA KA-7637
  • 2,4-DIMETHOXYBENZYLAMINE
  • (2,4-dimethoxyphenyl)methanamine
  • [(2,4-Dimethoxyphenyl)methyl]amine
  • 2,4-Dimethoxybenzenemethanamine
  • 2,4-Dimethyloxybenzylamine
CAS:
20781-20-8
MF:
C9H13NO2
MW:
167.21
EINECS:
672-586-1
Product Categories:
  • Chemical Amines
  • Aromatics
  • Amine
  • Amines
  • C9 to C10
  • Nitrogen Compounds
  • bc0001
Mol File:
20781-20-8.mol
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2,4-Dimethoxybenzylamine Chemical Properties

Boiling point:
95 °C0.2 mm Hg(lit.)
Density 
1.113 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.549(lit.)
Flash point:
>230 °F
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
form 
Liquid
pka
9.39±0.10(Predicted)
color 
Clear colorless to slightly yellow
Sensitive 
Air Sensitive
InChIKey
QOWBXWFYRXSBAS-UHFFFAOYSA-N
CAS DataBase Reference
20781-20-8(CAS DataBase Reference)
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Safety Information

Hazard Codes 
C
Risk Statements 
34
Safety Statements 
26-27-36/37/39-45
RIDADR 
UN 2735 8/PG 3
WGK Germany 
3
RTECS 
DP4430000
HazardClass 
8
PackingGroup 
III
HS Code 
29222990

MSDS

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2,4-Dimethoxybenzylamine Usage And Synthesis

Chemical Properties

Colorless to light yellow liqui

Uses

2,4-Dimethoxybenzylamine is an amine nucleophile used to investigate the 1,4- reactivity of 5-bromo-2-indene-1-one. It may be used in the following studies:

  • As an ammonia equivalent in the concise synthesis of a series of 2,4,5-trisubstituted oxazoles, via a tandem Ugi/Robinson-Gabriel reaction sequence.
  • Total synthesis of (-)-muraymycin (MRY) D2 and its epimer, the antibacterial nucleoside natural product.
  • Two-step synthesis of amide derivatives of uracil polyoxin C (UPOC) methyl ester using the Ugi reaction.
  • Synthesis of N-hydroxythiourea.
  • Synthesis of anti-HIV-1 agents.

General Description

2,4-Dimethoxybenzylamine can be preprepared by reduction (NaBH4 , BF3.OEt2, THF) of 2,4-dimethoxybenzonitrile.

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