A 201A
A 201A Basic information
- Product Name:
- A 201A
- Synonyms:
-
- A 201A
- Antibiotic 201A
- CAS:
- 37305-78-5
- MF:
- C37H50N6O14
- MW:
- 802.83
- Mol File:
- 37305-78-5.mol
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A 201A Usage And Synthesis
Description
A 201A is a nucleoside antibiotic isolated from Streptomyces capreolus.
Uses
A201A is a aminoacylnucleoside antibiotic with antibacterial activities. A201A is highly effective against Gram-positive and most Gram-negative anaerobic bacteria. A201A inhibits tRNA accommodation during translation[1][2].
References
[1] Nie S, et al. Total synthesis of nucleoside antibiotic A201A. J Am Chem Soc. 2014 Mar 19;136(11):4157-60. DOI:10.1021/ja501460j
[2] Wang J, et al. Bioinspired Total Synthesis of Complex Nucleoside Antibiotics A201A, A201D and A201E. Angew Chem Int Ed Engl. 2023 Jan 16;62(3):e202213810. DOI:10.1002/anie.202213810