Prolactin-Releasing Peptide (12-31), rat Chemical Properties

Density 

1.50±0.1 g/cm3(Predicted)

storage temp. 

−20°C

form 

Solid

color 

White to off-white

Sequence

Thr-Pro-Asp-Ile-Asn-Pro-Ala-Trp-Tyr-Thr-Gly-Arg-Gly-Ile-Arg-Pro-Val-Gly-Arg-Phe-NH2

Safety Information

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

Prolactin-Releasing Peptide (12-31), rat Usage And Synthesis

Uses

Prolactin-Releasing Peptide (12-31), rat is a fragment of the prolactin releasing peptide (PrRP). Prolactin-Releasing Peptide (12-31), rat shows high affinity for GPR10 receptors. Prolactin-Releasing Peptide (12-31), stimulates calcium mobilization in CHOK1 cells transfected with the PrRP receptor[1][2].

References

[1] Roland BL, et al. Anatomical distribution of prolactin-releasing peptide and its receptor suggests additional functions in the central nervous system and periphery. Endocrinology. 1999 Dec;140(12):5736-45. DOI:10.1210/endo.140.12.7211
[2] Langmead CJ, et al. Characterization of the binding of [(125)I]-human prolactin releasing peptide (PrRP) to GPR10, a novel G protein coupled receptor. Br J Pharmacol. 2000 Oct;131(4):683-8. DOI:10.1038/sj.bjp.0703617

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