8-(2-[7-NITRO-4-BENZOFURAZANYL]AMINOETHYLTHIO]GUANOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
8-(2-[7-NITRO-4-BENZOFURAZANYL]AMINOETHYLTHIO]GUANOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Basic information
- Product Name:
- 8-(2-[7-NITRO-4-BENZOFURAZANYL]AMINOETHYLTHIO]GUANOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
- Synonyms:
-
- 8-[[2-[(7-nitro-4-benzofurazanyl)amino]ethyl]thio]guanosine-3’,5’-cyclicmonophosphate(8-nbd-cgmp
- 8-NBD-CGMP, NA
- 8-NBD-CGMP SODIUM SALT
- 8-(2-[7-NITRO-4-BENZOFURAZANYL]AMINOETHYLTHIO]GUANOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
- GUANOSINE-3',5'-CYCLIC MONOPHOSPHATE, 8-[[2-[(7-NITRO-4-BENZOFURANZANYL)AMINO]ETHYL]THIO]-, SODIUM SALT
- 8-{{2-[(7-Nitro-4-benzofurazanyl)-amino]-ethyl}-thio}-guanosine-3'',5''-cycli
- Guanosine, 8-[[2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]ethyl]thio]-, cyclic 3',5'-(hydrogen phosphate) (9CI)
- 8-NBD-cGMP
- CAS:
- 115993-88-9
- MF:
- C18H18N9O10PS
- MW:
- 583.43
- Mol File:
- 115993-88-9.mol
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8-(2-[7-NITRO-4-BENZOFURAZANYL]AMINOETHYLTHIO]GUANOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Usage And Synthesis
Uses
8-NBD-cGMP is a fluorescent analog of cyclic guanosine monophosphate and a potent, membrane-permeable, fluorescent activator of cGMP-dependent protein kinase isozymes I α and I β. 8-NBD-cGMP is barely fluorescent in aqueous solution but fluoresces strongly in hydrophobic environments such as hydrophobic protein binding sites[1]
References
[1] Schmidpeter, et al. Ligand binding and activation properties of the purified bacterial cyclic nucleotide–gated channel SthK. Journal of General Physiology 150.6 (2018): 821-834. DOI:10.1085/jgp.201812023
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8-(2-[7-NITRO-4-BENZOFURAZANYL]AMINOETHYLTHIO]GUANOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT(115993-88-9)Related Product Information
- 8-(2-AMINOETHYLTHIO) GUANOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
- 5-AMINO-1-METHYL-2-(METHYLTHIO)-1H-IMIDAZOLE-4-CARBOXAMIDE
- 8-MERCAPTOGUANOSINE
- GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT
- 5-AMINO-2-MERCAPTO-1-METHYL-1H-IMIDAZOLE-4-CARBOXAMIDE
- 8-(2-[7-NITRO-4-BENZOFURAZANYL]AMINOETHYLTHIO]GUANOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
- 2'-DCGMP SODIUM SALT